ID   HUES 1
AC   CVCL_B139
SY   HUES-1; HUES1; HuES1; Hues1; HVRDe001-A
DR   EFO; EFO_0005355
DR   ENCODE; ENCBS771TSF
DR   ENCODE; ENCBS790PAZ
DR   ENCODE; ENCBS836MPJ
DR   GEO; GSM637758
DR   GEO; GSM1422443
DR   GEO; GSM1422444
DR   hPSCreg; HVRDe001-A
DR   ISCR; 102
DR   NIHhESC; NIHhESC-10-0014
DR   SKIP; SKIP001019
DR   SKIP; SKIP001905
DR   Wikidata; Q54896736
RX   PubMed=14999088;
RX   PubMed=17572666;
RX   PubMed=18772870;
RX   PubMed=19200798;
RX   PubMed=21295703;
RX   PubMed=21714037;
CC   From: Harvard University; Boston; USA.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0014.
CC   Registration: Swiss research registry; BAG-hES-IMP-0035.
CC   Registration: UK Stem Cell Bank (UKSCB); R-05-033, Steering comm. appl. SCSC04-25(1).
CC   Doubling time: 24 hours (PubMed=14999088).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
ST   Source(s): PubMed=19200798
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 11,12
ST   D16S539: 8,12
ST   D18S51: 13
ST   D21S11: 28,30
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 10
ST   D8S1179: 10,12
ST   FGA: 21,23
ST   Penta D: 9,12
ST   Penta E: 7,10
ST   TH01: 7,9
ST   TPOX: 8,9
ST   vWA: 17,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 25
//
RX   PubMed=14999088; DOI=10.1056/NEJMsr040330;
RA   Cowan C.A., Klimanskaya I.V., McMahon J., Atienza J., Witmyer J.,
RA   Zucker J.P., Wang S.-P., Morton C.C., McMahon A.P., Powers D.,
RA   Melton D.A.;
RT   "Derivation of embryonic stem-cell lines from human blastocysts.";
RL   N. Engl. J. Med. 350:1353-1356(2004).
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W.,
RA   Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B.,
RA   Brooking J., Chen K.G., Choo A.B.-H., Churchill G.A., Corbel M.,
RA   Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A.,
RA   Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S.,
RA   Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P.,
RA   Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K.,
RA   King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D.,
RA   Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M.,
RA   Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N.,
RA   O'Brien C.M., Oh S.K.-W., Olsson C., Otonkoski T., Park K.-Y.,
RA   Passier R., Patel H., Patel M.J., Pedersen R., Pera M.F.,
RA   Piekarczyk M.S., Reijo Pera R.A., Reubinoff B.E., Robins A.J.,
RA   Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H.,
RA   Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.T.,
RA   Tuuri T., van den Brink S., Vintersten K., Vuoristo S.,
RA   Ward-van Oostwaard D., Weaver T.A., Young L.A., Zhang W.-D.;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//
RX   PubMed=18772870; DOI=10.1038/nprot.2008.140;
RA   Braam S.R., Denning C., Matsa E., Young L.E., Passier R.,
RA   Mummery C.L.;
RT   "Feeder-free culture of human embryonic stem cells in conditioned
RT   medium for efficient genetic modification.";
RL   Nat. Protoc. 3:1435-1443(2008).
//
RX   PubMed=19200798; DOI=10.1016/j.stem.2008.12.001;
RA   Chen A.E., Egli D., Niakan K.K., Deng J., Akutsu H., Yamaki M.,
RA   Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.;
RT   "Optimal timing of inner cell mass isolation increases the efficiency
RT   of human embryonic stem cell derivation and allows generation of
RT   sibling cell lines.";
RL   Cell Stem Cell 4:103-106(2009).
//
RX   PubMed=21295703; DOI=10.1016/j.cell.2010.12.032;
RA   Bock C., Kiskinis E., Verstappen G., Gu H.-C., Boulting G.L., Smith Z.D.,
RA   Ziller M.J., Croft G.F., Amoroso M.W., Oakley D.H., Gnirke A.,
RA   Eggan K.C., Meissner A.;
RT   "Reference maps of human ES and iPS cell variation enable
RT   high-throughput characterization of pluripotent cell lines.";
RL   Cell 144:439-452(2011).
//
RX   PubMed=21714037; DOI=10.1002/stem.681;
RA   Ramirez J.-M., Gerbal-Chaloin S., Milhavet O., Qiang B., Becker F.,
RA   Assou S., Lemaitre J.-M., Hamamah S., De Vos J.;
RT   "Brief report: benchmarking human pluripotent stem cell markers during
RT   differentiation into the three germ layers unveils a striking
RT   heterogeneity: all markers are not equal.";
RL   Stem Cells 29:1469-1474(2011).
//