ID   1083-17-1A
AC   CVCL_B0T4
SY   17-1A; CO17-1A
DR   ABCD; ABCD_AC851
DR   Wikidata; Q108819344
RX   PubMed=94699;
RX   PubMed=286328;
RX   PubMed=6933502;
RX   PubMed=9806108;
CC   Biotechnology: Was used to produce the monoclonal antibody Edrecolomab (Panorex) which was evaluated as a therapeutic agent against stage III colorectal carcinoma. Was never approved by FDA but was used in Germany in 1995.
CC   Monoclonal antibody isotype: IgG2a.
CC   Monoclonal antibody target: UniProtKB; P16422; Human EPCAM/CD326.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_3411 ! P3X63Ag8
CA   Hybridoma
DT   Created: 23-09-21; Last updated: 21-03-23; Version: 4
//
RX   PubMed=94699; DOI=10.1007/BF01542654;
RA   Koprowski H., Steplewski Z., Mitchell K.F., Herlyn M., Herlyn D.,
RA   Fuhrer P.;
RT   "Colorectal carcinoma antigens detected by hybridoma antibodies.";
RL   Somatic Cell Genet. 5:957-971(1979).
//
RX   PubMed=286328; DOI=10.1073/pnas.76.3.1438;
RA   Herlyn M., Steplewski Z., Herlyn D., Koprowski H.;
RT   "Colorectal carcinoma-specific antigen: detection by means of
RT   monoclonal antibodies.";
RL   Proc. Natl. Acad. Sci. U.S.A. 76:1438-1442(1979).
//
RX   PubMed=6933502; DOI=10.1073/pnas.77.8.4539;
RA   Gilliland D.G., Steplewski Z., Collier R.J., Mitchell K.F.,
RA   Chang T.H., Koprowski H.;
RT   "Antibody-directed cytotoxic agents: use of monoclonal antibody to
RT   direct the action of toxin A chains to colorectal carcinoma cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 77:4539-4543(1980).
//
RX   PubMed=9806108; DOI=10.2165/00003495-199856040-00011;
RA   Adkins J.C., Spencer C.M.;
RT   "Edrecolomab (monoclonal antibody 17-1A).";
RL   Drugs 56:619-626(1998).
//