ID   UOK118
AC   CVCL_B097
SY   UOK-118; UOK 118
DR   Cosmic; 972871
DR   Cosmic; 972895
DR   Wikidata; Q54991328
RX   PubMed=1345811;
RX   PubMed=7915601;
RX   PubMed=8319216;
RX   PubMed=8493574;
CC   Sequence variation: Mutation; HGNC; HGNC:12687; VHL; Simple; p.Tyr175Thrfs*27 (c.523delT); Zygosity=Unspecified (PubMed=7915601; PubMed=8493574).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 13
//
RX   PubMed=1345811;
RA   Anglard P., Trahan E.E. Jr., Liu S., Latif F., Merino M.J., Lerman M.I.,
RA   Zbar B., Linehan W.M.;
RT   "Molecular and cellular characterization of human renal cell carcinoma
RT   cell lines.";
RL   Cancer Res. 52:348-356(1992).
//
RX   PubMed=7915601; DOI=10.1038/ng0594-85;
RA   Gnarra J.R., Tory K., Weng Y.-K., Schmidt L.S., Wei M.H., Li H., Latif F.,
RA   Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.-S.R., Florence C.,
RA   Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H.,
RA   Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B.,
RA   Linehan W.M.;
RT   "Mutations of the VHL tumour suppressor gene in renal carcinoma.";
RL   Nat. Genet. 7:85-90(1994).
//
RX   PubMed=8319216;
RA   Reiter R.E., Anglard P., Liu S., Gnarra J.R., Linehan W.M.;
RT   "Chromosome 17p deletions and p53 mutations in renal cell carcinoma.";
RL   Cancer Res. 53:3092-3097(1993).
//
RX   PubMed=8493574; DOI=10.1126/science.8493574;
RA   Latif F., Tory K., Gnarra J.R., Yao M., Duh F.-M., Orcutt M.L.,
RA   Stackhouse T., Kuzmin I.A., Modi W.S., Geil L., Schmidt L.S., Zhou F.-W.,
RA   Li H., Wei M.H., Chen F., Glenn G., Choyke P., Walther M.M., Weng Y.-K.,
RA   Duan D.-S.R., Dean M., Glavac D., Richards F.M., Crossey P.A.,
RA   Ferguson-Smith M.A., Le Paslier D., Chumakov I., Cohen D.,
RA   Chinault A.C., Maher E.R., Linehan W.M., Zbar B., Lerman M.I.;
RT   "Identification of the von Hippel-Lindau disease tumor suppressor
RT   gene.";
RL   Science 260:1317-1320(1993).
//