ID   UOK111
AC   CVCL_B090
SY   UOK-111; UOK 111; UOK 39
DR   cancercelllines; CVCL_B090
DR   Cosmic; 972892
DR   IARC_TP53; 722
DR   SKY/M-FISH/CGH; 1526
DR   Wikidata; Q54991285
RX   PubMed=1345811;
RX   PubMed=7915601;
RX   PubMed=8319216;
RX   PubMed=12759923;
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Val173Gly (c.518T>G); ClinVar=VCV000376016; Zygosity=Unspecified (PubMed=8319216).
CC   Sequence variation: Mutation; HGNC; 12687; VHL; Simple; p.Trp117Arg (c.349T>A); Zygosity=Unspecified (PubMed=7915601).
CC   Misspelling: Re-111; IARC_TP53=722; Note=Not really a misspelling but an assignment of a name based on first author of publication because assignment of correct cell line name was not done correctly.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 13
//
RX   PubMed=1345811;
RA   Anglard P., Trahan E.E. Jr., Liu S., Latif F., Merino M.J., Lerman M.I.,
RA   Zbar B., Linehan W.M.;
RT   "Molecular and cellular characterization of human renal cell carcinoma
RT   cell lines.";
RL   Cancer Res. 52:348-356(1992).
//
RX   PubMed=7915601; DOI=10.1038/ng0594-85;
RA   Gnarra J.R., Tory K., Weng Y., Schmidt L.S., Wei M.H., Li H., Latif F.,
RA   Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.R., Florence C.,
RA   Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H.,
RA   Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B.,
RA   Linehan W.M.;
RT   "Mutations of the VHL tumour suppressor gene in renal carcinoma.";
RL   Nat. Genet. 7:85-90(1994).
//
RX   PubMed=8319216;
RA   Reiter R.E., Anglard P., Liu S., Gnarra J.R., Linehan W.M.;
RT   "Chromosome 17p deletions and p53 mutations in renal cell carcinoma.";
RL   Cancer Res. 53:3092-3097(1993).
//
RX   PubMed=12759923; DOI=10.1002/gcc.10209;
RA   Pavlovich C.P., Padilla-Nash H.M., Wangsa D., Nickerson M.L.,
RA   Matrosova V., Linehan W.M., Ried T., Phillips J.L.;
RT   "Patterns of aneuploidy in stage IV clear cell renal cell carcinoma
RT   revealed by comparative genomic hybridization and spectral
RT   karyotyping.";
RL   Genes Chromosomes Cancer 37:252-260(2003).
//