ID   UOK111
AC   CVCL_B090
SY   UOK-111; UOK 111; UOK 39
DR   cancercelllines; CVCL_B090
DR   Cosmic; 972892
DR   IARC_TP53; 722
DR   SKY/M-FISH/CGH; 1526
DR   Wikidata; Q54991285
RX   PubMed=1345811;
RX   PubMed=7915601;
RX   PubMed=8319216;
RX   PubMed=12759923;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val173Gly (c.518T>G); ClinVar=VCV000376016; Zygosity=Unspecified (PubMed=8319216).
CC   Sequence variation: Mutation; HGNC; HGNC:12687; VHL; Simple; p.Trp117Arg (c.349T>A); Zygosity=Unspecified (PubMed=7915601).
CC   Misspelling: Re-111; IARC_TP53=722; Note=Not really a misspelling but an assignment of a name based on first author of publication because assignment of correct cell line name was not done correctly.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 14
//
RX   PubMed=1345811;
RA   Anglard P., Trahan E.E. Jr., Liu S., Latif F., Merino M.J., Lerman M.I.,
RA   Zbar B., Linehan W.M.;
RT   "Molecular and cellular characterization of human renal cell carcinoma
RT   cell lines.";
RL   Cancer Res. 52:348-356(1992).
//
RX   PubMed=7915601; DOI=10.1038/ng0594-85;
RA   Gnarra J.R., Tory K., Weng Y.-K., Schmidt L.S., Wei M.H., Li H., Latif F.,
RA   Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.-S.R., Florence C.,
RA   Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H.,
RA   Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B.,
RA   Linehan W.M.;
RT   "Mutations of the VHL tumour suppressor gene in renal carcinoma.";
RL   Nat. Genet. 7:85-90(1994).
//
RX   PubMed=8319216;
RA   Reiter R.E., Anglard P., Liu S., Gnarra J.R., Linehan W.M.;
RT   "Chromosome 17p deletions and p53 mutations in renal cell carcinoma.";
RL   Cancer Res. 53:3092-3097(1993).
//
RX   PubMed=12759923; DOI=10.1002/gcc.10209;
RA   Pavlovich C.P., Padilla-Nash H.M., Wangsa D., Nickerson M.L.,
RA   Matrosova V., Linehan W.M., Ried T., Phillips J.L.;
RT   "Patterns of aneuploidy in stage IV clear cell renal cell carcinoma
RT   revealed by comparative genomic hybridization and spectral
RT   karyotyping.";
RL   Genes Chromosomes Cancer 37:252-260(2003).
//