ID   UOK110
AC   CVCL_B089
SY   UOK-110; UOK 110
DR   cancercelllines; CVCL_B089
DR   Cosmic; 972891
DR   IARC_TP53; 721
DR   Wikidata; Q54991282
RX   PubMed=1345811;
RX   PubMed=7915601;
RX   PubMed=8319216;
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Val173Gly (c.518T>G); ClinVar=VCV000376016; Zygosity=Unspecified (PubMed=8319216).
CC   Sequence variation: Mutation; HGNC; 12687; VHL; Simple; p.Gly114Ser (c.340G>A); ClinVar=VCV000583094; Zygosity=Unspecified (PubMed=7915601).
CC   Misspelling: Re-110; IARC_TP53=721; Note=Not really a misspelling but an assignment of a name based on first author of publication because assignment of correct cell line name was not done correctly.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 13
//
RX   PubMed=1345811;
RA   Anglard P., Trahan E.E. Jr., Liu S., Latif F., Merino M.J., Lerman M.I.,
RA   Zbar B., Linehan W.M.;
RT   "Molecular and cellular characterization of human renal cell carcinoma
RT   cell lines.";
RL   Cancer Res. 52:348-356(1992).
//
RX   PubMed=7915601; DOI=10.1038/ng0594-85;
RA   Gnarra J.R., Tory K., Weng Y., Schmidt L.S., Wei M.H., Li H., Latif F.,
RA   Liu S., Chen F., Duh F.-M., Lubensky I.A., Duan D.R., Florence C.,
RA   Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H.,
RA   Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B.,
RA   Linehan W.M.;
RT   "Mutations of the VHL tumour suppressor gene in renal carcinoma.";
RL   Nat. Genet. 7:85-90(1994).
//
RX   PubMed=8319216;
RA   Reiter R.E., Anglard P., Liu S., Gnarra J.R., Linehan W.M.;
RT   "Chromosome 17p deletions and p53 mutations in renal cell carcinoma.";
RL   Cancer Res. 53:3092-3097(1993).
//