ID   C3842
AC   CVCL_B042
SY   C-3842
DR   BTO; BTO_0003567
DR   Cosmic; 1602480
DR   Wikidata; Q54808151
RX   PubMed=15731924;
RX   PubMed=22057234;
CC   Doubling time: ~10 days (PubMed=15731924).
CC   Sequence variation: Mutation; HGNC; HGNC:5382; IDH1; None_reported; -; Zygosity=- (PubMed=22057234).
CC   Sequence variation: Mutation; HGNC; HGNC:5383; IDH2; None_reported; -; Zygosity=- (PubMed=22057234).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=15731924).
CC   Derived from site: In situ; Bone, right proximal tibia; UBERON=UBERON_0008772.
DI   NCIt; C27482; Secondary chondrosarcoma
DI   NCIt; C3008; Enchondromatosis
DI   ORDO; Orphanet_55880; Chondrosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   38Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 17
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RX   PubMed=15731924; DOI=10.1007/s00428-004-1194-y;
RA   Kalinski T., Krueger S., Pelz A.-F., Wieacker P.F., Hartig R., Ropke M.,
RA   Schneider-Stock R., Dombrowski F., Roessner A.;
RT   "Establishment and characterization of the permanent human cell line
RT   C3842 derived from a secondary chondrosarcoma in Ollier's disease.";
RL   Virchows Arch. 446:287-299(2005).
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RX   PubMed=22057234; DOI=10.1038/ng.1004; PMCID=PMC3427908;
RA   Marfatia T., van Eijk R., d'Adamo P., van Ruler M.A.J.H.,
RA   Kuijjer M.L., Oosting J., Cleton-Jansen A.-M., van Oosterwijk J.G.,
RA   Verbeke S.L.J., Meijer D., van Wezel T., Nord K.H., Sangiorgi L.,
RA   Toker B., Liegl-Atzwanger B., San-Julian M., Sciot R., Limaye N.,
RA   Kindblom L.-G., Daugaard S., Godfraind C., Boon L.M., Vikkula M.,
RA   Kurek K.C., Szuhai K., French P.J., Bovee J.V.M.G.;
RT   "Somatic mosaic IDH1 and IDH2 mutations are associated with
RT   enchondroma and spindle cell hemangioma in Ollier disease and Maffucci
RT   syndrome.";
RL   Nat. Genet. 43:1256-1261(2011).
//