ID   A2780/AD10
AC   CVCL_B037
SY   A2780-AD10; A2780-AD-10; AD10; AD-10
DR   BTO; BTO:0004037
DR   cancercelllines; CVCL_B037
DR   Wikidata; Q54606588
RX   PubMed=8557231;
RX   PubMed=9554442;
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
CC   Sequence variation: Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
DI   NCIt; C7979; Ovarian endometrioid adenocarcinoma
DI   ORDO; Orphanet_454723; Endometrioid carcinoma of ovary
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0134 ! A2780
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 15
//
RX   PubMed=8557231; DOI=10.1006/gyno.1996.0014;
RA   Skilling J.S., Squatrito R.C., Connor J.P., Niemann T., Buller R.E.;
RT   "p53 gene mutation analysis and antisense-mediated growth inhibition
RT   of human ovarian carcinoma cell lines.";
RL   Gynecol. Oncol. 60:72-80(1996).
//
RX   PubMed=9554442; DOI=10.1093/jnci/90.8.597;
RA   Sabichi A.L., Hendricks D.T., Bober M.A., Birrer M.J.;
RT   "Retinoic acid receptor beta expression and growth inhibition of
RT   gynecologic cancer cells by the synthetic retinoid N-(4-hydroxyphenyl)
RT   retinamide.";
RL   J. Natl. Cancer Inst. 90:597-605(1998).
//