ID   ES2
AC   CVCL_AX39
SY   ES-2
DR   cancercelllines; CVCL_AX39
DR   Cosmic; 684054
DR   Cosmic; 2228223
DR   GEO; GSM1676356
DR   GEO; GSM1701686
DR   Progenetix; CVCL_AX39
DR   Wikidata; Q54832635
RX   PubMed=25010205;
RX   PubMed=26351324;
CC   Sequence variation: Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 3 fusion (Ex10/Ex6) (PubMed=25010205).
CC   Sequence variation: Mutation; HGNC; HGNC:11355; STAG2; Simple; p.Glu523Ter (c.1567G>T); Zygosity=Unspecified (PubMed=25010205).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (PubMed=25010205).
ST   Source(s): PubMed=25010205
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 13,14
ST   D16S539: 13
ST   D18S51: 13,19
ST   D19S433: 14
ST   D21S11: 29,30.2
ST   D2S1338: 18,20
ST   D3S1358: 16
ST   D5S818: 11
ST   D7S820: 10
ST   FGA: 24
ST   TH01: 6,9
ST   TPOX: 8
DI   NCIt; C4817; Ewing sarcoma
DI   ORDO; Orphanet_319; Ewing sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 19-12-24; Version: 12
//
RX   PubMed=25010205; DOI=10.1371/journal.pgen.1004475; PMCID=PMC4091782;
RA   Brohl, Andrew S.
RA   Solomon, David A.
RA   Chang, Wendy
RA   Wang, Jian-Jun
RA   Song, Young
RA   Sindiri, Sivasish
RA   Patidar, Rajesh
RA   Hurd, Laura
RA   Chen, Li
RA   Shern, Jack F.
RA   Liao, Hong-Ling
RA   Wen, Xin-Yu
RA   Gerard, Julia
RA   Kim, Jung-Sik
RA   Lopez-Guerrero, Jose Antonio
RA   Machado, Isidro
RA   Wai, Daniel H.
RA   Picci, Piero
RA   Triche, Timothy J.
RA   Horvai, Andrew E.
RA   Miettinen, Markku Martti
RA   Wei, Jun S.
RA   Catchpoole, Daniel
RA   Llombart-Bosch, Antonio
RA   Waldman, Todd A.
RA   Khan, Javed
RT   "The genomic landscape of the Ewing sarcoma family of tumors reveals
RT   recurrent STAG2 mutation.";
RL   PLoS Genet. 10:e1004475.1-e1004475.13(2014).
//
RX   PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074; PMCID=PMC4636476;
RA   Teicher, Beverly A.
RA   Polley, Eric C.
RA   Kunkel, Mark W.
RA   Evans, David
RA   Silvers, Thomas E.
RA   Delosh, Rene M.
RA   Laudeman, Julie
RA   Ogle, Chad
RA   Reinhart, Russell
RA   Selby, Michael
RA   Connelly, John
RA   Harris, Erik
RA   Monks, Anne
RA   Morris, Joel
RT   "Sarcoma cell line screen of oncology drugs and investigational agents
RT   identifies patterns associated with gene and microRNA expression.";
RL   Mol. Cancer Ther. 14:2452-2462(2015).
//