ID   BDEneu
AC   CVCL_AS29
DR   Wikidata; Q54795815
RX   PubMed=16344070;
RX   PubMed=18081149;
CC   Doubling time: ~17-19 hours (PubMed=18081149).
CC   Genetic integration: Method=Transduction; Gene=RGD; 2561; Erbb2 (Note=With p.Val661Glu).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: Activated Erbb2/neu.
CC   Derived from site: In situ; Bile duct; UBERON=UBERON_0002394.
CC   Cell type: Cholangiocyte; CL=CL_1000488.
CC   Breed/subspecies: Fischer 344; RS=RS_0000215.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_AS28 ! BDE1
SX   Male
AG   8-10W
CA   Transformed cell line
DT   Created: 02-05-16; Last updated: 14-08-25; Version: 12
//
RX   PubMed=18081149; DOI=10.1002/hep.22088;
RA   Sirica, Alphonse Eugene
RA   Zhang, Zi-Chen
RA   Lai, Guan-Hua
RA   Asano, Toru
RA   Shen, Xue-Ning
RA   Ward, Deanna J.
RA   Mahatme, Arvind
RA   DeWitt, Jennifer L.
RT   "A novel 'patient-like' model of cholangiocarcinoma progression based
RT   on bile duct inoculation of tumorigenic rat cholangiocyte cell
RT   lines.";
RL   Hepatology 47:1178-1190(2008).
//
RX   PubMed=16344070; DOI=10.1053/j.gastro.2005.10.010;
RA   Lai, Guan-Hua
RA   Zhang, Zi-Chen
RA   Shen, Xue-Ning
RA   Ward, Deanna J.
RA   DeWitt, Jennifer L.
RA   Holt, Shawn E.
RA   Rozich, Rebecca A.
RA   Hixson, Douglas Carter
RA   Sirica, Alphonse Eugene
RT   "erbB-2/neu transformed rat cholangiocytes recapitulate key cellular
RT   and molecular features of human bile duct cancer.";
RL   Gastroenterology 129:2047-2057(2005).
//