ID   HeLa-Mitotrap
DR   ECACC; 15042201
DR   Wikidata; Q54882721
DR   Ximbio; 152426
RX   PubMed=20159602;
CC   Population: African American.
CC   Characteristics: Can be used to determine the function of a protein by rapidly inactivating the protein of interest by rapamycin-induced rerouting to the mitochondria. This process is termed 'knocksideway'.
CC   Characteristics: Transfected with Mitotrap, a construct composed of the import signal of yeast TOM70, a YFP and the rapamycin-binding (FRB) domain from MTOR.
CC   Transfected with: HGNC; 3942; MTOR (with Met1_Arg2018del and Gln2114_Trp2549del = FRB).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_R965 ! HeLa M
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 02-05-24; Version: 12
RX   PubMed=20159602; DOI=10.1016/j.devcel.2009.12.015;
RA   Robinson M.S., Sahlender D.A., Foster S.D.;
RT   "Rapid inactivation of proteins by rapamycin-induced rerouting to
RT   mitochondria.";
RL   Dev. Cell 18:324-331(2010).