ID   COG-N-291
AC   CVCL_AQ18
DR   Wikidata; Q54813985
RX   PubMed=24792489;
RX   PubMed=28636942;
CC   Characteristics: Has long and heterogeneous telomeres and no telomerase activity. Its telomeres shortens continuously at an average rate of 80 base pairs per population doubling (PubMed=28636942).
CC   Doubling time: 3.4 days (PubMed=28636942); 224 hours (COG).
ST   Source(s): COG
ST   Amelogenin: X
ST   CSF1PO: 11,13
ST   D13S317: 12,13
ST   D16S539: 11,12
ST   D18S51: 12,15
ST   D19S433: 13,14
ST   D21S11: 29
ST   D2S1338: 19,23
ST   D3S1358: 16
ST   D5S818: 11
ST   D7S820: 11,12
ST   D8S1179: 12,14
ST   FGA: 21,22
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 16,17
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Children
CA   Cancer cell line
DT   Created: 02-05-16; Last updated: 05-10-23; Version: 7
//
RX   PubMed=24792489; DOI=10.1007/s11060-014-1456-8;
RA   Farooqi A.S., Dagg R.A., Choi L.M.R., Shay J.W., Reynolds C.P.,
RA   Lau L.M.S.;
RT   "Alternative lengthening of telomeres in neuroblastoma cell lines is
RT   associated with a lack of MYCN genomic amplification and with p53
RT   pathway aberrations.";
RL   J. Neurooncol. 119:17-26(2014).
//
RX   PubMed=28636942; DOI=10.1016/j.celrep.2017.05.087;
RA   Dagg R.A., Pickett H.A., Neumann A.A., Napier C.E., Henson J.D.,
RA   Teber E.T., Arthur J.W., Reynolds C.P., Murray J., Haber M.,
RA   Sobinoff A.P., Lau L.M.S., Reddel R.R.;
RT   "Extensive proliferation of human cancer cells with ever-shorter
RT   telomeres.";
RL   Cell Rep. 19:2544-2556(2017).
//