ID   HEK-Blue TGF-beta
AC   CVCL_A8CZ
DR   InvivoGen; hkb-tgfb
DR   Wikidata; Q107115284
CC   Characteristics: Designed to detect bioactive TGF-beta by monitoring the activation of the TGF-beta/SMAD pathway (InvivoGen=hkb-tgfb).
CC   Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of a beta-globin minimal promoter fused to 3 SMAD3/4-binding elements (SBE) (InvivoGen=hkb-tgfb).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:439; ALPP.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6769; SMAD3.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6770; SMAD4.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11772; TGFBR1.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Discontinued: InvivoGen; hkb-tgfb; true.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 20-05-21; Last updated: 10-04-25; Version: 10
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