ID   HEK-Blue ISG-KO-STING
AC   CVCL_A8BR
DR   InvivoGen; hkb-isgkostg
DR   Wikidata; Q107115269
CC   Characteristics: Specifically designed to study the STING/TBK1/IRF3 signaling pathway. Can detect bioactive type I IFNs through the activation of the JAK-STAT-IRF9 (InvivoGen=hkb-isgkostg).
CC   Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of an ISG54 minimal promoter in conjunction with 5 IFN-stimulated response elements (ISRE) (InvivoGen=hkb-isgkostg).
CC   Knockout cell: Method=Not specified; HGNC; HGNC:27962; STING1.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:439; ALPP.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_A8BQ ! HEK-Blue ISG
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 20-05-21; Last updated: 10-04-25; Version: 7
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