ID   WM793-P1N3
AC   CVCL_A802
SY   793-P1-N3
DR   cancercelllines; CVCL_A802
DR   Wikidata; Q54994315
RX   PubMed=8160777;
CC   Population: Caucasian.
CC   Characteristics: Established after 1 passage of WM793 co-injected with Matrigel into nude mice.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1773; CDK4; Simple; p.Lys22Gln (c.64A>C); ClinVar=VCV000485487; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Trp274Ter (c.821G>A); ClinVar=VCV001762511; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_8787 ! WM793
SX   Male
AG   37Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 15
//
RX   PubMed=8160777; PMCID=PMC1887247;
RA   Kobayashi H., Man S., MacDougall J.R., Graham C.H., Lu C.,
RA   Kerbel R.S.;
RT   "Variant sublines of early-stage human melanomas selected for
RT   tumorigenicity in nude mice express a multicytokine-resistant
RT   phenotype.";
RL   Am. J. Pathol. 144:776-786(1994).
//