ID   SCCNij185
AC   CVCL_A7DU
DR   cancercelllines; CVCL_A7DU
DR   Wikidata; Q107116856
RX   PubMed=33802339;
CC   Characteristics: Established from a xenograft maintained in mouse.
CC   Sequence variation: Mutation; HGNC; HGNC:6342; KIT; Simple; p.His708Asn (c.2122C>A); Zygosity=Unspecified (PubMed=33802339).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Unspecified (PubMed=33802339).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro153Serfs*13 (c.457_469del); Zygosity=Unspecified; Note=Splice acceptor mutation (PubMed=33802339).
CC   Derived from site: In situ; Larynx, supraglottis; UBERON=UBERON_0036263.
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 19-12-24; Version: 6
//
RX   PubMed=33802339; DOI=10.3390/cancers13051069; PMCID=PMC7959143;
RA   Gottgens E.-L., Ansems M., Leenders W.P.J., Bussink J., Span P.N.;
RT   "Genotyping and characterization of HPV status, hypoxia, and
RT   radiosensitivity in 22 head and neck cancer cell lines.";
RL   Cancers (Basel) 13:1069.1-1069.12(2021).
//