ID   eIF2ak(4KO)
AC   CVCL_A7BH
SY   Eif2ak 4KO MEF
DR   RCB; RCB4718
DR   Wikidata; Q107114859
RX   PubMed=27633668;
CC   Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1353448; Eif2ak1.
CC   Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1353449; Eif2ak2.
CC   Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1341830; Eif2ak3.
CC   Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1353427; Eif2ak4.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: C57BL/6J.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_A7BM ! WT(MEF) SV40-immortalized
SX   Sex unspecified
AG   13-14FD
CA   Transformed cell line
DT   Created: 20-05-21; Last updated: 29-06-23; Version: 5
CH   CVCL_A7BL ! eIF2ak(4KO+GCN2)
CH   CVCL_A7BI ! eIF2ak(4KO+HRI)
CH   CVCL_A7BJ ! eIF2ak(4KO+PERK)
CH   CVCL_A7BK ! eIF2ak(4KO+PKR)
//
RX   PubMed=27633668; DOI=10.1038/srep32886; PMCID=PMC5025754;
RA   Taniuchi, Shusuke
RA   Miyake, Masato
RA   Tsugawa, Kazue
RA   Oyadomari, Miho
RA   Oyadomari, Seiichi
RT   "Integrated stress response of vertebrates is regulated by four
RT   eIF2alpha kinases.";
RL   Sci. Rep. 6:32886.1-32886.11(2016).
//