ID   MEF_Hsp47 WT-1
AC   CVCL_A7BC
DR   RCB; RCB5291
DR   Wikidata; Q107116343
RX   PubMed=10995453;
RX   PubMed=16525016;
CC   Characteristics: Control cell line for MEF_Hsp47 KO-11 (Cellosaurus=CVCL_A7BD) and MEF_Hsp47 KO-13 (Cellosaurus=CVCL_A7BE).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   8-9FD
CA   Spontaneously immortalized cell line
DT   Created: 20-05-21; Last updated: 29-06-23; Version: 6
//
RX   PubMed=10995453; DOI=10.1083/jcb.150.6.1499; PMCID=PMC2150697;
RA   Nagai, Naoko
RA   Hosokawa, Masanori
RA   Itohara, Shigeyoshi
RA   Adachi, Eijiro
RA   Matsushita, Takatoshi
RA   Hosokawa, Nobuko
RA   Nagata, Kazuhiro
RT   "Embryonic lethality of molecular chaperone hsp47 knockout mice is
RT   associated with defects in collagen biosynthesis.";
RL   J. Cell Biol. 150:1499-1506(2000).
//
RX   PubMed=16525016; DOI=10.1091/mbc.e05-11-1065; PMCID=PMC1446091;
RA   Ishida, Yoshihito
RA   Kubota, Hiroshi
RA   Yamamoto, Akitsugu
RA   Kitamura, Akira
RA   Bachinger, Hans Peter
RA   Nagata, Kazuhiro
RT   "Type I collagen in Hsp47-null cells is aggregated in endoplasmic
RT   reticulum and deficient in N-propeptide processing and
RT   fibrillogenesis.";
RL   Mol. Biol. Cell 17:2346-2355(2006).
//