ID   DFCI024
AC   CVCL_A762
SY   DFCI 024; DFCI.024; Dana-Farber Cancer Institute 024
DR   Cosmic; 1165894
DR   DepMap; ACH-001058
DR   GEO; GSM794264
DR   PharmacoDB; DFCI024_289_2019
DR   Wikidata; Q54831032
RX   PubMed=18594010;
RX   PubMed=20679594;
RX   PubMed=26929325;
RX   PubMed=28196595;
RX   PubMed=29681454;
RX   PubMed=31068700;
WW   Info; MCLP; -; https://tcpaportal.org/mclp/
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: MD Anderson Cell Lines Project.
CC   HLA typing: A*24:02,33:01:01; B*04:02:01,35:02:01; C*08:02,04:01:01 (PubMed=26929325).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Proteomics; Expression; Reverse-phase protein array.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; SNP array analysis.
CC   Discontinued: DepMap; ACH-001058; true.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
ST   Source(s): PubMed=20679594
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 11,12
ST   D16S539: 8,13
ST   D5S818: 10,12
ST   D7S820: 9
ST   TH01: 6,9.3
ST   TPOX: 12
ST   vWA: 16,18
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 18
//
RX   PubMed=18594010; DOI=10.1158/1078-0432.CCR-08-0168; PMCID=PMC3025451;
RA   Koivunen, Jussi P.
RA   Mermel, Craig H.
RA   Zejnullahu, Kreshnik
RA   Murphy, Carly
RA   Lifshits, Eugene
RA   Holmes, Alison J.
RA   Choi, Hwan Geun
RA   Kim, Jhingook
RA   Chiang, Derek Y.
RA   Thomas, Roman Kurt
RA   Lee, Jinseon
RA   Richards, William G.
RA   Sugarbaker, David John
RA   Ducko, Christopher Thomas
RA   Lindeman, Neal I.
RA   Marcoux, J. Paul 2nd
RA   Engelman, Jeffrey Adam
RA   Gray, Nathanael S.
RA   Lee, Charles
RA   Meyerson, Matthew Langer
RA   Janne, Pasi Antero
RT   "EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung
RT   cancer.";
RL   Clin. Cancer Res. 14:4275-4283(2008).
//
RX   PubMed=20679594; DOI=10.1093/jnci/djq279; PMCID=PMC2935474;
RA   Gazdar, Adi F.
RA   Girard, Luc
RA   Lockwood, William W.
RA   Lam, Wan L.
RA   Minna, John D.
RT   "Lung cancer cell lines as tools for biomedical discovery and
RT   research.";
RL   J. Natl. Cancer Inst. 102:1310-1321(2010).
//
RX   PubMed=26929325; DOI=10.1073/pnas.1521812113; PMCID=PMC4801290;
RA   Tripathi, Satyendra C.
RA   Peters, Haley L.
RA   Taguchi, Ayumu
RA   Katayama, Hiroyuki
RA   Wang, Hong
RA   Momin, Amin
RA   Jolly, Mohit Kumar
RA   Celiktas, Muge
RA   Rodriguez-Canales, Jaime
RA   Liu, Hui
RA   Behrens, Carmen
RA   Wistuba, Ignacio Ivan
RA   Ben-Jacob, Eshel
RA   Levine, Herbert
RA   Molldrem, Jeffrey Joel
RA   Hanash, Samir M.
RA   Ostrin, Edwin Justin
RT   "Immunoproteasome deficiency is a feature of non-small cell lung
RT   cancer with a mesenchymal phenotype and is associated with a poor
RT   outcome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 113:E1555-E1564(2016).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076;
RA   Li, Jun
RA   Zhao, Wei
RA   Akbani, Rehan
RA   Liu, Wen-Bin
RA   Ju, Zhen-Lin
RA   Ling, Shi-Yun
RA   Vellano, Christopher P.
RA   Roebuck, Paul
RA   Yu, Qing-Hua
RA   Eterovic, A. Karina
RA   Byers, Lauren Averett
RA   Davies, Michael A.
RA   Deng, Wan-Leng
RA   Gopal, Y.N. Vashisht
RA   Chen, Guo
RA   von Euw, Erika Maria
RA   Slamon, Dennis Joseph
RA   Conklin, Dylan
RA   Heymach, John Victor
RA   Gazdar, Adi F.
RA   Minna, John D.
RA   Myers, Jeffrey N.
RA   Lu, Yi-Ling
RA   Mills, Gordon B.
RA   Liang, Han
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//
RX   PubMed=29681454; DOI=10.1016/j.cell.2018.03.028; PMCID=PMC5935540;
RA   McMillan, Elizabeth A.
RA   Ryu, Myung-Jeom
RA   Diep, Caroline H.
RA   Mendiratta, Saurabh
RA   Clemenceau, Jean Rene
RA   Vaden, Rachel M.
RA   Kim, Ju-Hwa
RA   Motoyaji, Takashi
RA   Covington, Kyle R.
RA   Peyton, Michael
RA   Huffman, Kenneth
RA   Wu, Xiao-Feng
RA   Girard, Luc
RA   Sung, Yeojin
RA   Chen, Pei-Hsaun
RA   Mallipeddi, Prema Latha
RA   Lee, Joo Young
RA   Hanson, Jordan
RA   Voruganti, Sukesh
RA   Yu, Yunku
RA   Park, Sunho
RA   Sudderth, Jessica
RA   DeSevo, Christopher
RA   Muzny, Donna M.
RA   Doddapaneni, HarshaVardhan
RA   Gazdar, Adi F.
RA   Gibbs, Richard Alexander
RA   Hwang, Tae Hyun
RA   Heymach, John Victor
RA   Wistuba, Ignacio Ivan
RA   Coombes, Kevin Robert
RA   Williams, Noelle S.
RA   Wheeler, David A.
RA   MacMillan, John B.
RA   DeBerardinis, Ralph J.
RA   Roth, Michael G.
RA   Posner, Bruce Arthur
RA   Minna, John D.
RA   Kim, Hyun Seok
RA   White, Michael A.
RT   "Chemistry-first approach for nomination of personalized treatment in
RT   lung cancer.";
RL   Cell 173:864-878.e29(2018).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103;
RA   Ghandi, Mahmoud
RA   Huang, Franklin W.
RA   Jane-Valbuena, Judit
RA   Kryukov, Gregory V.
RA   Lo, Christopher C.
RA   McDonald, E. Robert 3rd
RA   Barretina, Jordi Ginesta
RA   Gelfand, Ellen T.
RA   Bielski, Craig M.
RA   Li, Hao-Xin
RA   Hu, Kevin
RA   Andreev-Drakhlin, Alexander Y.
RA   Kim, Jaegil
RA   Hess, Julian M.
RA   Haas, Brian J.
RA   Aguet, Francois
RA   Weir, Barbara A.
RA   Rothberg, Michael V.
RA   Paolella, Brenton R.
RA   Lawrence, Michael Scott
RA   Akbani, Rehan
RA   Lu, Yi-Ling
RA   Tiv, Hong L.
RA   Gokhale, Prafulla C.
RA   de Weck, Antoine
RA   Mansour, Ali Amin
RA   Oh, Coyin
RA   Shih, Juliann
RA   Hadi, Kevin
RA   Rosen, Yanay
RA   Bistline, Jonathan
RA   Venkatesan, Kavitha
RA   Reddy, Anupama
RA   Sonkin, Dmitriy
RA   Liu, Manway
RA   Lehar, Joseph
RA   Korn, Joshua M.
RA   Porter, Dale A.
RA   Jones, Michael D.
RA   Golji, Javad
RA   Caponigro, Giordano
RA   Taylor, Jordan E.
RA   Dunning, Caitlin M.
RA   Creech, Amanda L.
RA   Warren, Allison C.
RA   McFarland, James M.
RA   Zamanighomi, Mahdi
RA   Kauffmann, Audrey
RA   Stransky, Nicolas
RA   Imielinski, Marcin
RA   Maruvka, Yosef E.
RA   Cherniack, Andrew D.
RA   Tsherniak, Aviad
RA   Vazquez, Francisca
RA   Jaffe, Jacob D.
RA   Lane, Andrew Alan
RA   Weinstock, David M.
RA   Johannessen, Cory M.
RA   Morrissey, Michael P.
RA   Stegmeier, Frank
RA   Schlegel, Robert
RA   Hahn, William Chun
RA   Getz, Gad
RA   Mills, Gordon B.
RA   Boehm, Jesse S.
RA   Golub, Todd Robert
RA   Garraway, Levi Alexander
RA   Sellers, William Raj
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//