ID   SMKT-R2
AC   CVCL_A750
SY   SMKT-R-2; SMKT R2; SMKTR2
DR   Cosmic; 849380
DR   Wikidata; Q54954962
RX   PubMed=1433606;
RX   PubMed=2051699;
RX   PubMed=2815432;
RX   PubMed=11146448;
RX   PubMed=24477694;
RX   PubMed=27993170;
CC   Population: Japanese.
CC   Characteristics: Established from a xenotransplantable tumor at passage 2 in a nude mouse (PubMed=2815432).
CC   Doubling time: 56.4 hours (PubMed=2815432).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   79Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 13
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RX   PubMed=1433606; DOI=10.1016/S0022-5347(17)37026-X;
RA   Tsukamoto T., Kumamoto Y., Miyao N., Masumori N., Takahashi A.,
RA   Yanase M.;
RT   "Interleukin-6 in renal cell carcinoma.";
RL   J. Urol. 148:1778-1781(1992).
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RX   PubMed=2051699; DOI=10.5980/jpnjurol1989.82.613;
RA   Otani N., Tsukamoto T., Kumamoto Y., Miyao N.;
RT   "Study on in vitro invasive potential of renal cell carcinoma cell
RT   lines and effect of growth factors (EGF and TGF-beta 1) on their in
RT   invasions.";
RL   Nihon Hinyokika Gakkai Zasshi 82:613-619(1991).
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RX   PubMed=2815432; DOI=10.1007/BF00262990;
RA   Miyao N., Tsukamoto T., Kumamoto Y.;
RT   "Establishment of three human renal cell carcinoma cell lines (SMKT-R-1,
RT   SMKT-R-2, and SMKT-R-3) and their characters.";
RL   Urol. Res. 17:317-324(1989).
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RX   PubMed=11146448; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1034>3.0.CO;2-S;
RA   Kondo K.-i., Yao M., Kobayashi K., Ota S., Yoshida M., Kaneko S.,
RA   Baba M., Sakai N., Kishida T., Kawakami S., Uemura H., Nagashima Y.,
RA   Nakatani Y., Hosaka M.;
RT   "PTEN/MMAC1/TEP1 mutations in human primary renal-cell carcinomas and
RT   renal carcinoma cell lines.";
RL   Int. J. Cancer 91:219-224(2001).
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RX   PubMed=24477694; DOI=10.1007/s00432-014-1593-7;
RA   Tanaka T., Torigoe T., Hirohashi Y., Sato E., Honma I., Kitamura H.,
RA   Masumori N., Tsukamoto T., Sato N.;
RT   "Hypoxia-inducible factor (HIF)-independent expression mechanism and
RT   novel function of HIF prolyl hydroxylase-3 in renal cell carcinoma.";
RL   J. Cancer Res. Clin. Oncol. 140:503-513(2014).
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RX   PubMed=27993170; DOI=10.1186/s12943-016-0565-8;
RA   Brodaczewska K.K., Szczylik C., Fiedorowicz M., Porta C.,
RA   Czarnecka A.M.;
RT   "Choosing the right cell line for renal cell cancer research.";
RL   Mol. Cancer 15:83.1-83.15(2016).
//