ID   ATL-21C(-)/2
AC   CVCL_A6TI
DR   RCB; RCB3552
DR   Wikidata; Q107113392
RX   PubMed=32210945;
CC   Population: Japanese.
CC   Characteristics: Lost its original IL2 dependency. Cultured for 2 years without IL2.
CC   Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
CC   Donor information: Established from a patient suffering from adult T-cell leukemia/lymphoma (ATLL).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_VQ15 ! ATL-21C
SX   Sex unspecified
AG   Adult
CA   Transformed cell line
DT   Created: 20-05-21; Last updated: 29-06-23; Version: 7
//
RX   PubMed=32210945; DOI=10.3389/fmicb.2020.00356; PMCID=PMC7067701;
RA   Maeda, Michiyuki
RA   Tanabe-Shibuya, Junko
RA   Miyazato, Paola
RA   Masutani, Hiroshi
RA   Yasunaga, Jun-ichirou
RA   Usami, Kazumasa
RA   Shimizu, Akira
RA   Matsuoka, Masao
RT   "IL-2/IL-2 receptor pathway plays a crucial role in the growth and
RT   malignant transformation of HTLV-1-infected T cells to develop adult
RT   T-cell leukemia.";
RL   Front. Microbiol. 11:356.1-356.17(2020).
//