ID   Tet-293/Ins6
AC   CVCL_A6AC
SY   tet-293/Ins6; tet293/Ins6
DR   Wikidata; Q107117028
RX   PubMed=11925627;
CC   Characteristics: Secretes insulin induced by doxycyclin.
CC   Characteristics: Transfected with reverse tetracycline-controlled transactivator (rtTA), a fusion between a mutated version of E.coli TetR and the activating domain of HSV-1 VP16.
CC   Transfected with: HGNC; 6081; INS.
CC   Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_KS31 ! HEK 293 Tet-On
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 20-05-21; Last updated: 05-10-23; Version: 6
//
RX   PubMed=11925627; DOI=10.3748/wjg.v8.i2.367;
RA   Qin X.-Y., Shen K.-T., Zhang X., Cheng Z.-H., Xu X.-R., Han Z.-G.;
RT   "Establishment of an artificial beta-cell line expressing insulin
RT   under the control of doxycycline.";
RL   World J. Gastroenterol. 8:367-370(2002).
//