ID   SCMC-RM2
AC   CVCL_A667
AS   CVCL_UF93
SY   SCMC-RM-2; SCMC-R-2; SCMCRM2; Saitama Children's Medical Center-RhabdoMyosarcoma 2
DR   cancercelllines; CVCL_A667
DR   Cell_Model_Passport; SIDM01346
DR   Cosmic; 687965
DR   Cosmic; 801761
DR   Cosmic; 1037300
DR   Cosmic; 1048113
DR   Cosmic; 1718359
DR   Cosmic; 2355929
DR   DepMap; ACH-001184
DR   GEO; GSM219592
DR   GEO; GSM1012754
DR   JCRB; NIHS0044
DR   Wikidata; Q54952464
RX   CelloPub=CLPUB00110;
RX   CelloPub=CLPUB00599;
RX   DOI=10.2198/sbk.34.289;
RX   PubMed=2323848;
RX   PubMed=18082704;
RX   PubMed=19235922;
RX   PubMed=22142829;
RX   PubMed=23578105;
RX   PubMed=23882450;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Population: Japanese.
CC   Doubling time: 50 hours (PubMed=2323848).
CC   Sequence variation: Gene fusion; HGNC; HGNC:3819; FOXO1 + HGNC; HGNC:8617; PAX3; Name(s)=PAX3-FOXO1, PAX3-FKHR; Note=Not found in original tumor (PubMed=23578105; CelloPub=CLPUB00599).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; SNP array analysis.
CC   Misspelling: SCMC-RMZ; PubMed=19235922.
CC   Discontinued: JCRB; NIHS0044; true.
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): DepMap=ACH-001184
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 9,11,12
ST   D16S539: 10,11
ST   D18S51: 11,13
ST   D21S11: 30,33.2
ST   D3S1358: 15,16
ST   D5S818: 11,12
ST   D7S820: 11,12
ST   D8S1179: 14,15
ST   FGA: 19,27
ST   Penta D: 9
ST   Penta E: 11,20,22
ST   TH01: 6,9
ST   TPOX: 8
ST   vWA: 14,18
DI   NCIt; C8971; Embryonal rhabdomyosarcoma
DI   ORDO; Orphanet_99757; Embryonal rhabdomyosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   11Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 25
CH   CVCL_A668 ! SCMC-RM2-1
//
RX   CelloPub=CLPUB00599;
RA   Sugimoto, Tohru
RA   Kuroda, Hiroshi
RA   Kuwahara, Yasumichi
RA   Katsumi, Yoshiki
RA   Misawa, Akiko
RA   Moritake, Hiroshi
RA   Hosoi, Hajime
RT   "Cellular and molecular characteristics of established childhood
RT   soft-tissue sarcoma cell lines.";
RL   J. Cancer Res. Therap. Oncol. 7:202.1-202.12(2019).
//
RX   DOI=10.2198/sbk.34.289;
RA   Mizusawa, Hiroshi
RT   "Operation of the JCRB cell bank and isoenzyme.";
RL   Seibutsu Butsuri Kagaku 34:289-292(1990).
//
RX   PubMed=2323848; DOI=10.1002/ijc.2910450423;
RA   Hayashi, Yasuhide
RA   Sugimoto, Tohru
RA   Horii, Yoshihiro
RA   Hosoi, Hajime
RA   Inazawa, Johji
RA   Kemshead, John T.
RA   Inaba, Toshiya
RA   Hanada, Ryoji
RA   Yamamoto, Keiko
RA   Gown, Allen M.
RA   Sawada, Tadashi
RT   "Characterization of an embryonal rhabdomyosarcoma cell line showing
RT   amplification and over-expression of the N-myc oncogene.";
RL   Int. J. Cancer 45:705-711(1990).
//
RX   PubMed=19235922; DOI=10.1002/gcc.20655;
RA   Missiaglia, Edoardo
RA   Selfe, Joanna
RA   Hamdi, Mohamed
RA   Williamson, Daniel
RA   Schaaf, Gerben
RA   Fang, Cheng
RA   Koster, Jan
RA   Summersgill, Brenda M.
RA   Messahel, Boo
RA   Versteeg, Rogier
RA   Pritchard-Jones, Kathryn
RA   Kool, Marcel
RA   Shipley, Janet M.
RT   "Genomic imbalances in rhabdomyosarcoma cell lines affect expression
RT   of genes frequently altered in primary tumors: an approach to identify
RT   candidate genes involved in tumor development.";
RL   Genes Chromosomes Cancer 48:455-467(2009).
//
RX   PubMed=18082704; DOI=10.1016/j.jpedsurg.2007.08.026;
RA   Komuro, Hiroaki
RA   Saihara, Ryoko
RA   Shinya, Miki
RA   Takita, Junko
RA   Kaneko, Setsuko
RA   Kaneko, Michio
RA   Hayashi, Yasuhide
RT   "Identification of side population cells (stem-like cell population)
RT   in pediatric solid tumor cell lines.";
RL   J. Pediatr. Surg. 42:2040-2045(2007).
//
RX   PubMed=23578105; DOI=10.1111/cas.12173; PMCID=PMC7657110;
RA   Nishimura, Riki
RA   Takita, Junko
RA   Sato-Otsubo, Aiko
RA   Kato, Motohiro
RA   Koh, Katsuyoshi
RA   Hanada, Ryoji
RA   Tanaka, Yukichi
RA   Kato, Keisuke
RA   Maeda, Daichi
RA   Fukayama, Masashi
RA   Sanada, Masashi
RA   Hayashi, Yasuhide
RA   Ogawa, Seishi
RT   "Characterization of genetic lesions in rhabdomyosarcoma using a
RT   high-density single nucleotide polymorphism array.";
RL   Cancer Sci. 104:856-864(2013).
//
RX   CelloPub=CLPUB00110;
RA   Hayashi, Yasuhide
RA   Hanada, Ryoji
RA   Moriwaki, Kouichi
RA   Yamamoto, Keiko
RA   Imaizumi, Satohiko
RA   Hirata, Akinari
RA   Nishida, Toshiro
RT   "Establishment and characterization of cell lines derived from
RT   malignant tumors in children.";
RL   Saitama Shoni Iryo Senta Igaku-shi 8:16-23(1991).
//
RX   PubMed=22142829; DOI=10.1158/1078-0432.CCR-11-2056; PMCID=PMC3271129;
RA   Shukla, Neerav
RA   Ameur, Nabahet
RA   Yilmaz, Ismail
RA   Nafa, Khedoudja
RA   Lau, Chyau-Yueh
RA   Marchetti, Angela
RA   Borsu, Laetitia
RA   Barr, Frederic G.
RA   Ladanyi, Marc
RT   "Oncogene mutation profiling of pediatric solid tumors reveals
RT   significant subsets of embryonal rhabdomyosarcoma and neuroblastoma
RT   with mutated genes in growth signaling pathways.";
RL   Clin. Cancer Res. 18:748-757(2012).
//
RX   PubMed=23882450; DOI=10.3389/fonc.2013.00183; PMCID=PMC3713458;
RA   Hinson, Ashley R.P.
RA   Jones, Rosanne
RA   Crose, Lisa E.S.
RA   Belyea, Brian C.
RA   Barr, Frederic G.
RA   Linardic, Corinne Mary
RT   "Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research:
RT   utility and pitfalls.";
RL   Front. Oncol. 3:183.1-183.12(2013).
//