ID   JBL-2
AC   CVCL_A630
SY   JBL2; Japanese Burkitt's Lymphoma 2
DR   Cosmic; 931123
DR   Wikidata; Q54898529
RX   PubMed=467575;
RX   PubMed=1395095;
RX   PubMed=2470097;
RX   PubMed=2847931;
RX   PubMed=3024964;
RX   PubMed=3026973;
RX   PubMed=3027441;
RX   PubMed=6327071;
RX   PubMed=6806672;
RX   PubMed=7064731;
RX   PubMed=7464876;
RX   PubMed=9473234;
RX   PubMed=22120970;
RX   PubMed=24590883;
CC   Population: Japanese.
CC   Sequence variation: Gene fusion; HGNC; HGNC:5715; IGK + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGK (PubMed=6806672; PubMed=22120970).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   29Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 17
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RX   PubMed=467575; DOI=10.1007/BF01968217;
RA   Miyoshi I., Hiraki S., Kimura I., Miyamoto K., Sato J.;
RT   "2/8 translocation in a Japanese Burkitt's lymphoma.";
RL   Experientia 35:742-743(1979).
//
RX   PubMed=1395095; DOI=10.1111/j.1365-2249.1992.tb05846.x; PMCID=PMC1554548;
RA   Leduc I., Preud'homme J.-L., Cogne M.;
RT   "Structure and expression of the mb-1 transcript in human lymphoid
RT   cells.";
RL   Clin. Exp. Immunol. 90:141-146(1992).
//
RX   PubMed=2470097; DOI=10.1073/pnas.86.9.3257; PMCID=PMC287109;
RA   Shtivelman E., Henglein B., Groitl P., Lipp M., Bishop J.M.;
RT   "Identification of a human transcription unit affected by the variant
RT   chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:3257-3260(1989).
//
RX   PubMed=2847931; DOI=10.1002/eji.1830181003;
RA   Cogne M., Mounir S., Preud'homme J.-L., Nau F., Guglielmi P.;
RT   "Burkitt's lymphoma cell lines producing truncated mu immunoglobulin
RT   heavy chains lacking part of the variable region.";
RL   Eur. J. Immunol. 18:1485-1489(1988).
//
RX   PubMed=3024964; DOI=10.1002/j.1460-2075.1986.tb04578.x; PMCID=PMC1167233;
RA   Graham M., Adams J.M.;
RT   "Chromosome 8 breakpoint far 3' of the c-myc oncogene in a Burkitt's
RT   lymphoma 2;8 variant translocation is equivalent to the murine pvt-1
RT   locus.";
RL   EMBO J. 5:2845-2851(1986).
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RX   PubMed=3026973; DOI=10.1002/ijc.2910390215;
RA   Ehlin-Henriksson B., Manneborg-Sandlund A., Klein G.;
RT   "Expression of B-cell-specific markers in different Burkitt lymphoma
RT   subgroups.";
RL   Int. J. Cancer 39:211-218(1987).
//
RX   PubMed=3027441; DOI=10.1093/jnci/78.2.235;
RA   Cohen J.H.M., Revillard J.-P., Magaud J.-P., Lenoir G.M., Vuillaume M.,
RA   Manel A.-M., Vincent C., Bryon P.-A.;
RT   "B-cell maturation stages of Burkitt's lymphoma cell lines according
RT   to Epstein-Barr virus status and type of chromosome translocation.";
RL   J. Natl. Cancer Inst. 78:235-242(1987).
//
RX   PubMed=6327071; DOI=10.1016/0092-8674(84)90381-7;
RA   Taub R., Kelly K., Battey J., Latt S.A., Lenoir G.M., Tantravahi U.,
RA   Tu Z.-M., Leder P.;
RT   "A novel alteration in the structure of an activated c-myc gene in a
RT   variant t(2;8) Burkitt lymphoma.";
RL   Cell 37:511-520(1984).
//
RX   PubMed=6806672; DOI=10.1038/298474a0;
RA   Lenoir G.M., Preud'homme J.-L., Bernheim A., Berger R.;
RT   "Correlation between immunoglobulin light chain expression and variant
RT   translocation in Burkitt's lymphoma.";
RL   Nature 298:474-476(1982).
//
RX   PubMed=7064731; DOI=10.18926/AMO/30706;
RA   Hamasaki K.;
RT   "Chromosome abnormalities in Japanese Burkitt lymphoma cell lines.";
RL   Acta Med. Okayama 36:23-38(1982).
//
RX   PubMed=7464876; DOI=10.1056/NEJM198103193041221;
RA   Miyoshi I., Hamasaki K., Miyamoto K., Nagase K., Narahara K.,
RA   Kitajima K., Kimura I., Sato J.;
RT   "Chromosome translocations in Burkitt's lymphoma.";
RL   N. Engl. J. Med. 304:734-734(1981).
//
RX   PubMed=9473234; DOI=10.1182/blood.V91.5.1680;
RA   Klangby U., Okan I., Magnusson K.P., Wendland M., Lind P., Wiman K.G.;
RT   "p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a
RT   mRNA and protein expression in Burkitt's lymphoma.";
RL   Blood 91:1680-1687(1998).
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RX   PubMed=22120970; DOI=10.1002/gcc.21915;
RA   Kroenlein H., Schwartz S., Reinhardt R., Rieder H., Molkentin M.,
RA   Gokbuget N., Hoelzer D., Thiel E., Burmeister T.;
RT   "Molecular analysis of the t(2;8)/MYC-IGK translocation in high-grade
RT   lymphoma/leukemia by long-distance inverse PCR.";
RL   Genes Chromosomes Cancer 51:290-299(2012).
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RX   PubMed=24590883; DOI=10.1002/gcc.22161;
RA   Murga Penas E.-M., Schilling G., Behrmann P., Klokow M.,
RA   Vettorazzi E., Bokemeyer C., Dierlamm J.;
RT   "Comprehensive cytogenetic and molecular cytogenetic analysis of 44
RT   Burkitt lymphoma cell lines: secondary chromosomal changes
RT   characterization, karyotypic evolution, and comparison with primary
RT   samples.";
RL   Genes Chromosomes Cancer 53:497-515(2014).
//