ID   HU-3
AC   CVCL_A619
DR   Cosmic; 787436
DR   Cosmic; 975255
DR   Cosmic; 1012070
DR   Cosmic; 1281318
DR   Cosmic; 2306210
DR   Wikidata; Q54896687
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=9096695;
RX   PubMed=9406997;
RX   PubMed=16408098;
CC   Characteristics: CSF2 dependent (PubMed=9406997).
CC   Doubling time: 60 +- 11 hours (PubMed=9096695).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C7965; Adult acute megakaryoblastic leukemia
DI   ORDO; Orphanet_518; Acute megakaryoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 14-08-25; Version: 11
CH   CVCL_E9WZ ! HU-3 clone D3
CH   CVCL_E9X0 ! HU-3 clone D7
CH   CVCL_E9X1 ! HU-3 clone E11
CH   CVCL_E9X2 ! HU-3 clone E6
CH   CVCL_E9X3 ! HU-3 clone F5
CH   CVCL_E9X4 ! HU-3 clone G3
CH   CVCL_E9X5 ! HU-3 clone G5
CH   CVCL_E9X6 ! HU-3 clone H7
CH   CVCL_E9X7 ! HU-3 clone H9
CH   CVCL_RM04 ! HU-3/TPO
//
RX   PubMed=9406997;
RA   Morgan, Doris A.
RA   Class, Reiner
RA   Soslau, Gerald
RA   Brodsky, Isadore
RT   "Cytokine-mediated erythroid maturation in megakaryoblastic human cell
RT   line HU-3.";
RL   Exp. Hematol. 25:1378-1385(1997).
//
RX   PubMed=16408098; DOI=10.1038/sj.leu.2404081;
RA   Quentmeier, Hilmar
RA   MacLeod, Roderick A.F.
RA   Zaborski, Margarete
RA   Drexler, Hans Gunther
RT   "JAK2 V617F tyrosine kinase mutation in cell lines derived from
RT   myeloproliferative disorders.";
RL   Leukemia 20:471-476(2006).
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler, Hans Gunther
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=9096695; DOI=10.1038/sj.leu.2400621;
RA   Drexler, Hans Gunther
RA   Zaborski, Margarete
RA   Quentmeier, Hilmar
RT   "Thrombopoietin supports the continuous growth of cytokine-dependent
RT   human leukemia cell lines.";
RL   Leukemia 11:541-551(1997).
//