ID   ARH-77 clone A5P3
AC   CVCL_A5YK
SY   ARH-77A5P3; A5P3
DR   Wikidata; Q107113379
RX   PubMed=8051085;
RX   PubMed=11001907;
CC   Problematic cell line: Misclassified. Parent cell line (ARH-77) was originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:1349162; Sdc1.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: B-cell; CL=CL_0000236.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1072 ! ARH-77
SX   Female
AG   33Y
CA   Transformed cell line
DT   Created: 20-05-21; Last updated: 14-08-25; Version: 8
//
RX   PubMed=11001907; DOI=10.1182/blood.V96.7.2528;
RA   Borset, Magne
RA   Hjertner, Oyvind
RA   Yaccoby, Shmuel
RA   Epstein, Joshua
RA   Sanderson, Ralph D.
RT   "Syndecan-1 is targeted to the uropods of polarized myeloma cells
RT   where it promotes adhesion and sequesters heparin-binding proteins.";
RL   Blood 96:2528-2536(2000).
//
RX   PubMed=8051085; DOI=10.1016/S0021-9258(17)32120-8;
RA   Liebersbach, Brian F.
RA   Sanderson, Ralph D.
RT   "Expression of syndecan-1 inhibits cell invasion into type I
RT   collagen.";
RL   J. Biol. Chem. 269:20013-20019(1994).
//