ID   UT-SCC-59A
AC   CVCL_A5VI
SY   UT-SCC59A; University of Turku-Squamous Cell Carcinoma-59A
DR   Wikidata; Q107117368
RX   DOI=10.1158/1538-7445.AM2020-507;
RX   PubMed=22427941;
RX   PubMed=27305645;
RX   PubMed=28322200;
CC   Derived from site: Metastatic; Temple, skin; UBERON=UBERON_8480028.
DI   NCIt; C4819; Skin squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_A7EG ! UT-SCC-59B
OI   CVCL_A7EF ! UT-SCC-59C
SX   Male
AG   81Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 29-06-23; Version: 4
//
RX   DOI=10.1158/1538-7445.AM2020-507;
RA   Kondratyev M.K., Pesic A., Dvorkin-Sheva A., Ketela T., Moffat J.,
RA   Koritzinsky M., Wouters B.G.;
RT   "Repurposing of FDA approved drugs for treatment of metastatic HNSCC.";
RL   Cancer Res. 80 Suppl. 16:507-507(2020).
//
RX   PubMed=22427941; DOI=10.1371/journal.pone.0033041; PMCID=PMC3299721;
RA   Toriseva M., Ala-aho R., Peltonen S., Peltonen J., Grenman R.,
RA   Kahari V.-M.;
RT   "Keratinocyte growth factor induces gene expression signature
RT   associated with suppression of malignant phenotype of cutaneous
RT   squamous carcinoma cells.";
RL   PLoS ONE 7:e33041.1-e33041.16(2012).
//
RX   PubMed=27305645; DOI=10.1111/exd.13109;
RA   Farshchian M., Nissinen L., Grenman R., Kahari V.-M.;
RT   "Dasatinib promotes apoptosis of cutaneous squamous carcinoma cells by
RT   regulating activation of ERK1/2.";
RL   Exp. Dermatol. 26:89-92(2017).
//
RX   PubMed=28322200; DOI=10.1016/j.ajpath.2017.01.006;
RA   Riihila P., Nissinen L., Farshchian M., Kallajoki M., Kivisaari A.,
RA   Meri S., Grenman R., Peltonen S., Peltonen J., Pihlajaniemi T.,
RA   Heljasvaara R., Kahari V.-M.;
RT   "Complement component C3 and complement factor B promote growth of
RT   cutaneous squamous cell carcinoma.";
RL   Am. J. Pathol. 187:1186-1197(2017).
//