ID   SB-28-Ohlfest
AC   CVCL_A5ED
SY   SB-28; SB28
DR   DSMZ; ACC-880
DR   DSMZCellDive; ACC-880
DR   Wikidata; Q107116848
RX   PubMed=24878890;
RX   PubMed=30524896;
CC   Characteristics: Glioma was induced by intraventricular transfection of pT2/C-Luc/PGKp-SB100 and Sleeping Beauty (SB)-flanked pT2/CAG-NRasV12 and pT2/shp53/mPDGF.
CC   Doubling time: ~30 hours (DSMZ=ACC-880).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase.
CC   Omics: Genomics; Whole exome sequencing.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
CC   Breed/subspecies: C57BL/6.
DI   NCIt; C21938; Mouse glioblastoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
AG   <1D
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 10-04-25; Version: 7
//
RX   PubMed=24878890; DOI=10.1007/s00262-014-1561-8; PMCID=PMC4221287;
RA   Kosaka A., Ohkuri T., Okada H.;
RT   "Combination of an agonistic anti-CD40 monoclonal antibody and the
RT   COX-2 inhibitor celecoxib induces anti-glioma effects by promotion of
RT   type-1 immunity in myeloid cells and T-cells.";
RL   Cancer Immunol. Immunother. 63:847-857(2014).
//
RX   PubMed=30524896; DOI=10.1080/2162402X.2018.1501137; PMCID=PMC6279422;
RA   Genoud V., Marinari E., Nikolaev S.I., Castle J.C., Bukur V.,
RA   Dietrich P.-Y., Okada H., Walker P.R.;
RT   "Responsiveness to anti-PD-1 and anti-CTLA-4 immune checkpoint
RT   blockade in SB28 and GL261 mouse glioma models.";
RL   OncoImmunology 7:e1501137.1-e1501137.10(2018).
//