ID   A-431-Luc2
AC   CVCL_A4BS
DR   ATCC; CRL-1555-LUC2
DR   cancercelllines; CVCL_A4BS
DR   Wikidata; Q105506024
CC   Population: Caucasian.
CC   Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=CRL-1555-LUC2).
CC   Doubling time: ~22 hours (ATCC=CRL-1555-LUC2).
CC   Sequence variation: Gene fusion; HGNC; 3236; EGFR + HGNC; 9237; PPARGC1A; Name(s)=EGFR-PPARGC1A (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
CC   Transfected with: UniProtKB; P33967; B.cereus Bsr.
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
ST   Source(s): ATCC
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 9,13
ST   D16S539: 12,14
ST   D5S818: 12,13
ST   D7S820: 10
ST   TH01: 9
ST   TPOX: 11
ST   vWA: 15,17
DI   NCIt; C4819; Skin squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0037 ! A-431
SX   Female
AG   85Y
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 05-10-23; Version: 6
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