ID   TF-1-Luc2
AC   CVCL_A4BP
DR   ATCC; CRL-2003-LUC2
DR   cancercelllines; CVCL_A4BP
DR   Wikidata; Q105511173
CC   Population: Japanese.
CC   Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=CRL-2003-LUC2).
CC   Doubling time: ~19 hours (ATCC=CRL-2003-LUC2).
CC   Sequence variation: Gene fusion; HGNC; HGNC:15868; ABHD12 + HGNC; HGNC:1537; CBFA2T3; Name(s)=CBFA2T3-ABHD12 (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Pro (c.182A>C); ClinVar=VCV000280409; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile251Thrfs*94 (c.752delT); ClinVar=VCV001759367; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase (Note=With optimized codon usage for mammalian expression).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): ATCC=CRL-2003-LUC2
ST   Amelogenin: X,Y
ST   CSF1PO: 13
ST   D13S317: 8,9
ST   D16S539: 9,12
ST   D5S818: 13
ST   D7S820: 12
ST   TH01: 7,9
ST   TPOX: 8
ST   vWA: 15,17
DI   NCIt; C7152; Erythroleukemia
DI   ORDO; Orphanet_318; Acute erythroid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0559 ! TF-1
SX   Male
AG   35Y
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 10-04-25; Version: 9
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