ID   Agarabi CHO
AC   CVCL_A4AR
DR   ATCC; CRL-3440
DR   Wikidata; Q105506379
RX   PubMed=29086492;
CC   Characteristics: Parent cell line was stably transfected with a two-vector system expressing a model mouse-human chimeric IgG1 antibody.
CC   Doubling time: 22-28 hours (ATCC=CRL-3440).
CC   Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Homozygous (from parent cell line).
CC   Transformant: NCIt; C129640; Cobalt-60 gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_7180 ! CHO-DG44
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 12-01-21; Last updated: 19-12-24; Version: 6
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RX   PubMed=29086492; DOI=10.1002/btpr.2575; PMCID=PMC5821576;
RA   Velugula-Yellela S.R., Williams A., Trunfio N., Hsu C.-J., Chavez B.,
RA   Yoon S., Agarabi C.;
RT   "Impact of media and antifoam selection on monoclonal antibody
RT   production and quality using a high throughput micro-bioreactor
RT   system.";
RL   Biotechnol. Prog. 34:262-270(2018).
//