ID   KRC/Y
AC   CVCL_A448
SY   KRC-Y; KRC Y; KRCY
DR   cancercelllines; CVCL_A448
DR   Cosmic; 877457
DR   Cosmic; 1152535
DR   IARC_TP53; 5612
DR   Wikidata; Q38122405
RX   PubMed=3338971;
RX   PubMed=8621251;
RX   PubMed=10723130;
RX   PubMed=10929426;
CC   Population: Japanese.
CC   Doubling time: 73 hours (Note=At 15th passage) (PubMed=3338971).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys176Phe (c.527G>T); ClinVar=VCV000376569; Zygosity=Unspecified (PubMed=8621251).
CC   Misspelling: KRC; PubMed=10929426.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   41Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 16
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RX   PubMed=3338971; DOI=10.1007/BF02623810;
RA   Yano H., Maruiwa M., Sugihara S., Kojiro M., Noda S., Eto K.;
RT   "Establishment and characterization of a new human renal cell
RT   carcinoma cell line (KRC/Y).";
RL   In Vitro Cell. Dev. Biol. 24:9-16(1988).
//
RX   PubMed=8621251; DOI=10.1002/(SICI)1097-0215(19960503)66:3<322::AID-IJC9>3.0.CO;2-0;
RA   Tomita Y., Bilim V., Kawasaki T., Takahashi K., Okan I.,
RA   Magnusson K.P., Wiman K.G.;
RT   "Frequent expression of Bcl-2 in renal-cell carcinomas carrying
RT   wild-type p53.";
RL   Int. J. Cancer 66:322-325(1996).
//
RX   PubMed=10723130; DOI=10.1038/sj.onc.1203449;
RA   Alimov A., Kost-Alimova M., Liu J., Li C.-D., Bergerheim U.S.R.,
RA   Imreh S., Klein G., Zabarovsky E.R.;
RT   "Combined LOH/CGH analysis proves the existence of interstitial 3p
RT   deletions in renal cell carcinoma.";
RL   Oncogene 19:1392-1399(2000).
//
RX   PubMed=10929426; DOI=10.1007/s002400000103;
RA   Shintaku I., Kawagoe N., Yutani S., Hoshi S., Orikasa S.,
RA   Yoshizumi O., Itoh K.;
RT   "Expression of the SART1 tumor rejection antigen in renal cell
RT   carcinoma.";
RL   Urol. Res. 28:178-184(2000).
//