ID   UT-MUC-1
AC   CVCL_A438
SY   University of Turku-MUcoepidermoid Carcinoma-1
DR   Cosmic; 1520948
DR   Wikidata; Q54992047
RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RX   PubMed=1571132;
RX   PubMed=8725545;
RX   PubMed=8782485;
RX   PubMed=9187133;
RX   PubMed=16444749;
CC   Doubling time: 52 hours (Note=At 9th passage) (PubMed=1571132).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=8725545; PubMed=8782485).
CC   Derived from site: In situ; Oral cavity, hard palate; UBERON=UBERON_0003216.
DI   NCIt; C6214; Hard palate mucoepidermoid carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   74Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 14
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RX   DOI=10.1016/B978-0-12-333530-2.50007-1;
RA   Carey T.E.;
RT   "Head and neck tumor cell lines.";
RL   (In book chapter) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York; USA (1994).
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RX   PubMed=1571132; DOI=10.1001/archotol.1992.01880050096023;
RA   Grenman R., Pekkola-Heino K., Joensuu H., Aitasalo K., Klemi P.,
RA   Lakkala T.;
RT   "UT-MUC-1, a new mucoepidermoid carcinoma cell line, and its
RT   radiosensitivity.";
RL   Arch. Otolaryngol. Head Neck Surg. 118:542-547(1992).
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RX   PubMed=8725545; DOI=10.3109/00016489609137854;
RA   Pekkola-Heino K., Servomaa K., Kiuru A., Grenman R.;
RT   "Increased radiosensitivity is associated with p53 mutations in cell
RT   lines derived from oral cavity carcinoma.";
RL   Acta Oto-Laryngol. 116:341-344(1996).
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RX   PubMed=8782485; DOI=10.1046/j.1365-2184.1996.01009.x;
RA   Servomaa K., Kiuru A., Grenman R., Pekkola-Heino K., Pulkkinen J.O.,
RA   Rytomaa T.;
RT   "p53 mutations associated with increased sensitivity to ionizing
RT   radiation in human head and neck cancer cell lines.";
RL   Cell Prolif. 29:219-230(1996).
//
RX   PubMed=9187133;
RA   Soukka T., Salmi M., Joensuu H., Hakkinen L., Sointu P., Koulu L.,
RA   Kalimo K., Klemi P., Grenman R., Jalkanen S.T.;
RT   "Regulation of CD44v6-containing isoforms during proliferation of
RT   normal and malignant epithelial cells.";
RL   Cancer Res. 57:2281-2289(1997).
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RX   PubMed=16444749; DOI=10.1002/gcc.20306;
RA   Behboudi A., Enlund F., Winnes M., Andren Y., Nordkvist A., Leivo I.,
RA   Flaberg E., Szekely L., Makitie A.A., Grenman R., Mark J., Stenman G.;
RT   "Molecular classification of mucoepidermoid carcinomas-prognostic
RT   significance of the MECT1-MAML2 fusion oncogene.";
RL   Genes Chromosomes Cancer 45:470-481(2006).
//