ID   RB 4492
AC   CVCL_A2MV
SY   RB4492: ND5BE
DR   Wikidata; Q105510653
RX   Patent=US5773219;
RX   PubMed=3941662;
RX   PubMed=6621576;
RX   PubMed=6726265;
RX   PubMed=8643543;
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   69Y
CA   Finite cell line
DT   Created: 12-01-21; Last updated: 29-06-23; Version: 5
//
RX   Patent=US5773219;
RA   Sanford K.K., Parshad R., Robbins J.H.;
RT   "Process for detecting Alzheimer disease using cultured cells.";
RL   Patent number US5773219, 30-Jun-1998.
//
RX   PubMed=3941662; DOI=10.1016/0027-5107(86)90121-1;
RA   Scudiero D.A., Polinsky R.J., Brumback R.A., Tarone R.E., Nee L.E.,
RA   Robbins J.H.;
RT   "Alzheimer disease fibroblasts are hypersensitive to the lethal effects
RT   of a DNA-damaging chemical.";
RL   Mutat. Res. 159:125-131(1986).
//
RX   PubMed=6621576; DOI=10.1016/0027-5107(83)90010-6;
RA   Tarone R.E., Scudiero D.A., Robbins J.H.;
RT   "Statistical methods for in vitro cell survival assays.";
RL   Mutat. Res. 111:79-96(1983).
//
RX   PubMed=6726265; DOI=10.1136/jnnp.47.4.391; PMCID=PMC1027781;
RA   Robbins J.H., Scudiero D.A., Otsuka F., Tarone R.E., Brumback R.A.,
RA   Wirtschafter J.D., Polinsky R.J., Barrett S.F., Moshell A.N.,
RA   Scarpinato R.G., Ganges M.B., Nee L.E., Meyer S.A., Clatterbuck B.E.;
RT   "Hypersensitivity to DNA-damaging agents in cultured cells from
RT   patients with Usher's syndrome and Duchenne muscular dystrophy.";
RL   J. Neurol. Neurosurg. Psychiatry 47:391-398(1984).
//
RX   PubMed=8643543; DOI=10.1073/pnas.93.10.5146; PMCID=PMC39422;
RA   Parshad R., Sanford K.K., Price F.M., Melnick L.K., Nee L.E.,
RA   Schapiro M.B., Tarone R.E., Robbins J.H.;
RT   "Fluorescent light-induced chromatid breaks distinguish Alzheimer
RT   disease cells from normal cells in tissue culture.";
RL   Proc. Natl. Acad. Sci. U.S.A. 93:5146-5150(1996).
//