ID   MDCK2-ABCC2
AC   CVCL_A2JY
SY   MDCK-MRP2; ABCC2-MDCK2
DR   Wikidata; Q105510103
RX   PubMed=24056116;
RX   PubMed=25264565;
CC   Genetic integration: Method=Transfection; Gene=HGNC; 53; ABCC2.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Caution: There is another MDCK-II cell line with transfected human ABCC2: MDCK-MRP2 (Cellosaurus=CVCL_X022).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
CC   Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372.
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
HI   CVCL_0424 ! MDCK-II
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 12-01-21; Last updated: 10-09-24; Version: 7
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RX   PubMed=24056116; DOI=10.1097/RLI.0b013e3182a70043;
RA   Jia J., Puls D., Oswald S., Jedlitschky G., Kuhn J.-P., Weitschies W.,
RA   Hosten N., Siegmund W., Keiser M.;
RT   "Characterization of the intestinal and hepatic uptake/efflux
RT   transport of the magnetic resonance imaging contrast agent
RT   gadolinium-ethoxylbenzyl-diethylenetriamine-pentaacetic acid.";
RL   Invest. Radiol. 49:78-86(2014).
//
RX   PubMed=25264565; DOI=10.1111/bcp.12522; PMCID=PMC4345960;
RA   Siegmund W., Modess C., Scheuch E., Methling K., Keiser M., Nassif A.,
RA   Rosskopf D., Bednarski P.J., Borlak J., Terhaag B.;
RT   "Metabolic activation and analgesic effect of flupirtine in healthy
RT   subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1.";
RL   Br. J. Clin. Pharmacol. 79:501-513(2015).
//