ID   YUMMER1.7
AC   CVCL_A2AX
SY   Yale University Mouse Melanoma Exposed to Radiation 1.7
DR   Wikidata; Q105511840
RX   PubMed=28379630;
CC   Characteristics: The parent cell line was exposed to three rounds of UVB radiation at 1,500 J/m2 to generate a cell line with an increased number of somatic mutations (PubMed=28379630).
CC   Knockout cell: Method=KO mouse; MGI; MGI:104738; Cdkn2a.
CC   Knockout cell: Method=KO mouse; MGI; MGI:109583; Pten.
CC   Sequence variation: Mutation; MGI; MGI:88190; Braf; Simple; p.Val637Glu (c.1910T>A); Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCIt; C17231; Ultraviolet radiation.
CC   Breed/subspecies: C57BL/6.
DI   NCIt; C21790; Mouse melanoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_JK16 ! YUMM1.7
SX   Male
AG   Adult
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 21-03-23; Version: 3
//
RX   PubMed=28379630; DOI=10.1111/pcmr.12591; PMCID=PMC5820096;
RA   Wang J., Perry C.J., Meeth K., Thakral D., Damsky W., Micevic G.,
RA   Kaech S.M., Blenman K., Bosenberg M.W.;
RT   "UV-induced somatic mutations elicit a functional T cell response in
RT   the YUMMER1.7 mouse melanoma model.";
RL   Pigment Cell Melanoma Res. 30:428-435(2017).
//