ID   343T
AC   CVCL_A2AK
DR   cancercelllines; CVCL_A2AK
DR   Wikidata; Q105505909
RX   PubMed=10545285;
RX   PubMed=14978140;
RX   PubMed=18645002;
CC   From: Siegfried, Jill M.; University of Pittsburgh; Pittsburgh; USA.
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Unspecified (PubMed=18645002).
CC   Miscellaneous: Age/sex of donor and lung cancer type from personal communication of Siegfried, Jill M.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C9133; Lung adenosquamous carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   49Y
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 19-12-24; Version: 7
//
RX   PubMed=10545285; DOI=10.1006/pupt.1999.0210;
RA   Siegfried J.M., Krishnamachary N., Gaither Davis A.L., Gubish C.T.,
RA   Hunt J.D., Shriver S.P.;
RT   "Evidence for autocrine actions of neuromedin B and gastrin-releasing
RT   peptide in non-small cell lung cancer.";
RL   Pulm. Pharmacol. Ther. 12:291-302(1999).
//
RX   PubMed=14978140; DOI=10.4049/jimmunol.172.5.3319;
RA   Friedman R.S., Bangur C.S., Zasloff E.J., Fan L.-Q., Wang T.-T.,
RA   Watanabe Y., Kalos M.D.;
RT   "Molecular and immunological evaluation of the transcription factor
RT   SOX-4 as a lung tumor vaccine antigen.";
RL   J. Immunol. 172:3319-3327(2004).
//
RX   PubMed=18645002; DOI=10.1158/1535-7163.MCT-07-2169; PMCID=PMC2556508;
RA   Stabile L.P., Rothstein M.E., Keohavong P., Jin J., Yin J.-L.,
RA   Land S.R., Dacic S., Luong T.M., Kim K.J., Dulak A.M., Siegfried J.M.;
RT   "Therapeutic targeting of human hepatocyte growth factor with a single
RT   neutralizing monoclonal antibody reduces lung tumorigenesis.";
RL   Mol. Cancer Ther. 7:1913-1922(2008).
//