ID   KCL003
AC   CVCL_A239
SY   KCL003(CF1); KCL-003; CF-1; CF1; KCL003/CF-1; KCL-003-CF-1; KCL003_CF1; KCLe003-A
DR   hPSCreg; KCLe003-A
DR   SKIP; SKIP001882
DR   Wikidata; Q54899653
RX   PubMed=15820050;
RX   PubMed=17572666;
WW   Provider; KCL; -; https://www.kcl.ac.uk/research/stem-cell-research
WW   Provider; NIBSC; -; https://nibsc.org/science_and_research/advanced_therapies/uk_stem_cell_bank/cell_line_catalogue/research_grade_stem_cell_lines/laboratory_grade/kcl003-cf-1.aspx
CC   From: King's College London; London; United Kingdom.
CC   Registration: Swiss research registry; BAG-hES-IMP-0017.
CC   Registration: UK Stem Cell Bank (UKSCB); R-06-027, Steering comm. appl. SCSC-06-28(2).
CC   Sequence variation: Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=15820050).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 24
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RX   PubMed=15820050; DOI=10.1016/S1472-6483(10)61801-9;
RA   Pickering S.J., Minger S.L., Patel M.J., Taylor H., Black C.,
RA   Burns C.J., Ekonomou A., Braude P.R.;
RT   "Generation of a human embryonic stem cell line encoding the cystic
RT   fibrosis mutation deltaF508, using preimplantation genetic
RT   diagnosis.";
RL   Reprod. BioMed. Online 10:390-397(2005).
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W.,
RA   Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B.,
RA   Brooking J., Chen K.G., Choo A.B.-H., Churchill G.A., Corbel M.,
RA   Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A.,
RA   Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S.,
RA   Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P.,
RA   Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K.,
RA   King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D.,
RA   Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M.,
RA   Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N.,
RA   O'Brien C.M., Oh S.K.-W., Olsson C., Otonkoski T., Park K.-Y.,
RA   Passier R., Patel H., Patel M.J., Pedersen R., Pera M.F.,
RA   Piekarczyk M.S., Reijo Pera R.A., Reubinoff B.E., Robins A.J.,
RA   Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H.,
RA   Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.T.,
RA   Tuuri T., van den Brink S., Vintersten K., Vuoristo S.,
RA   Ward-van Oostwaard D., Weaver T.A., Young L.A., Zhang W.-D.;
RG   International Stem Cell Initiative;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//