ID   Hep-12
AC   CVCL_A1RS
DR   cancercelllines; CVCL_A1RS
DR   Wikidata; Q105507640
RX   Patent=CN101693886B;
RX   PubMed=19897602;
RX   PubMed=19929456;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, China General Microbiological Culture Collection Center; CGMCC No.3204.
CC   Population: Chinese.
CC   Doubling time: 53 hours (PubMed=19929456).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg249Ser (c.747G>T); ClinVar=VCV000012352; Zygosity=Unspecified (PubMed=19897602).
CC   Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
CC   Omics: Array-based CGH.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_A1RR ! Hep-11
SX   Male
AG   47Y
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 05-10-23; Version: 6
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RX   Patent=CN101693886B;
RA   Xing B.-C., Wang Y., Xu X.-L., Du X.-J., Ke Y.;
RT   "Liver cancer cell line and application thereof.";
RL   Patent number CN101693886B, 06-Jun-2012.
//
RX   PubMed=19897602; DOI=10.1093/carcin/bgp232;
RA   Xu X.-L., Xing B.-C., Han H.-B., Zhao W., Hu M.-H., Xu Z.-L., Li J.-Y.,
RA   Xie Y., Gu J., Wang Y., Zhang Z.-Q.;
RT   "The properties of tumor-initiating cells from a hepatocellular
RT   carcinoma patient's primary and recurrent tumor.";
RL   Carcinogenesis 31:167-174(2010).
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RX   PubMed=19929456; DOI=10.3109/14653240903390803;
RA   Xu X.-L., Xing B.-C., Hu M.-H., Xu Z.-L., Xie Y., Dai G.-H., Gu J.,
RA   Wang Y., Zhang Z.-Q.;
RT   "Recurrent hepatocellular carcinoma cells with stem cell-like
RT   properties: possible targets for immunotherapy.";
RL   Cytotherapy 12:190-200(2010).
//