ID   Pan2MmLuc
AC   CVCL_A1IJ
DR   cancercelllines; CVCL_A1IJ
DR   JCRB; NIHS1359
DR   Wikidata; Q102114733
RX   PubMed=30747829;
CC   Population: Japanese.
CC   Characteristics: Metastatic. Established from the orthopical implementation of the TCC-pan2 cell line in BALB/c nu/nu nude mice.
CC   Doubling time: ~24 hours (PubMed=30747829).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=30747829).
CC   Sequence variation: Gene deletion; HGNC; 6770; SMAD4; Zygosity=Homozygous (PubMed=30747829).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Heterozygous (PubMed=30747829).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; c.993+1G>A (IVS9+1G>A); ClinVar=VCV000528261; Zygosity=Homozygous; Note=Splice donor mutation (PubMed=30747829).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase.
CC   Discontinued: JCRB; NIHS1359; true.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_A1II ! Pan2M
SX   Female
AG   47Y
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 05-10-23; Version: 7
//
RX   PubMed=30747829; DOI=10.1097/MPA.0000000000001253;
RA   Yanagihara K., Kubo T., Mihara K., Kuwata T., Ochiai A., Seyama T.,
RA   Yokozaki H.;
RT   "Development and biological analysis of a novel orthotopic peritoneal
RT   dissemination mouse model generated using a pancreatic ductal
RT   adenocarcinoma cell line.";
RL   Pancreas 48:315-322(2019).
//