ID   Pan2M
AC   CVCL_A1II
DR   cancercelllines; CVCL_A1II
DR   Wikidata; Q102114732
RX   PubMed=30747829;
CC   Population: Japanese.
CC   Characteristics: Metastatic. Established from the orthopical implementation of the parent cell line in BALB/c nu/nu nude mice.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.993+1G>A (IVS9+1G>A); ClinVar=VCV000528261; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3178 ! TCC-Pan2
SX   Female
AG   47Y
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 19-12-24; Version: 8
CH   CVCL_A1IJ ! Pan2MmLuc
//
RX   PubMed=30747829; DOI=10.1097/MPA.0000000000001253; PMCID=PMC6426353;
RA   Yanagihara, Kazuyoshi
RA   Kubo, Takanori
RA   Mihara, Keichiro
RA   Kuwata, Takeshi
RA   Ochiai, Atsushi
RA   Seyama, Toshio
RA   Yokozaki, Hiroshi
RT   "Development and biological analysis of a novel orthotopic peritoneal
RT   dissemination mouse model generated using a pancreatic ductal
RT   adenocarcinoma cell line.";
RL   Pancreas 48:315-322(2019).
//