ID   WMN
AC   CVCL_A1FT
DR   Cosmic; 850213
DR   Wikidata; Q102115105
RX   PubMed=7757991;
RX   PubMed=8344493;
RX   PubMed=8402660;
RX   PubMed=9563901;
RX   PubMed=9787181;
RX   PubMed=10567774;
CC   Doubling time: 24 hours (PubMed=8402660).
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C2912; Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 10-04-25; Version: 5
//
RX   PubMed=7757991;
RA   Bae I., Fan S.-J., Bhatia K.G., Kohn K.W., Fornace A.J. Jr.,
RA   O'Connor P.M.;
RT   "Relationships between G1 arrest and stability of the p53 and
RT   p21Cip1/Waf1 proteins following gamma-irradiation of human lymphoma
RT   cells.";
RL   Cancer Res. 55:2387-2393(1995).
//
RX   PubMed=8344493; DOI=10.1096/fasebj.7.10.8344493;
RA   Bhatia K.G., Goldschmidts W., Gutierrez M.I., Gaidano G., Dalla-Favera R.,
RA   Magrath I.T.;
RT   "Hemi- or homozygosity: a requirement for some but not other p53
RT   mutant proteins to accumulate and exert a pathogenetic effect.";
RL   FASEB J. 7:951-956(1993).
//
RX   PubMed=8402660;
RA   O'Connor P.M., Jackman J., Jondle D., Bhatia K.G., Magrath I.T.,
RA   Kohn K.W.;
RT   "Role of the p53 tumor suppressor gene in cell cycle arrest and
RT   radiosensitivity of Burkitt's lymphoma cell lines.";
RL   Cancer Res. 53:4776-4780(1993).
//
RX   PubMed=9563901;
RA   Fan S.-J., Cherney B.W., Reinhold W.C., Rucker K., O'Connor P.M.;
RT   "Disruption of p53 function in immortalized human cells does not
RT   affect survival or apoptosis after taxol or vincristine treatment.";
RL   Clin. Cancer Res. 4:1047-1054(1998).
//
RX   PubMed=9787181; DOI=10.1182/blood.V92.9.3410;
RA   Sakai A., Thieblemont C., Wellmann A., Jaffe E.S., Raffeld M.;
RT   "PTEN gene alterations in lymphoid neoplasms.";
RL   Blood 92:3410-3415(1998).
//
RX   PubMed=10567774; DOI=10.1159/000007237;
RA   Fan S.-J., Duba D.E., O'Connor P.M.;
RT   "Cellular effects of olomoucine in human lymphoma cells differing in
RT   p53 function.";
RL   Chemotherapy 45:437-445(1999).
//