ID   VCaP AR-V7/pHag
AC   CVCL_A1BP
SY   VCaPAR-V7/pHag
DR   cancercelllines; CVCL_A1BP
DR   Wikidata; Q102115093
RX   PubMed=25008967;
CC   Population: Caucasian.
CC   Characteristics: Inducibly expresses AR variant 7 (ARv7).
CC   Virology: Contains an integrated xenotropic MuLV-related virus (XMRV) Bxv-1 (from parent cell line).
CC   Sequence variation: Gene fusion; HGNC; HGNC:3446; ERG + HGNC; HGNC:11876; TMPRSS2; Name(s)=TMPRSS2-ERG (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7127; MLH1; Simple; p.Ile219Val (c.655A>G); ClinVar=VCV000036557; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:644; AR (Note=Isoform ARv7).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Bone, vertebra; UBERON=UBERON_0002412.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2235 ! VCaP
SX   Male
AG   59Y
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 19-12-24; Version: 11
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RX   PubMed=25008967; DOI=10.1016/j.biocel.2014.06.013; PMCID=PMC4160387;
RA   Krause W.C., Shafi A.A., Nakka M., Weigel N.L.;
RT   "Androgen receptor and its splice variant, AR-V7, differentially
RT   regulate FOXA1 sensitive genes in LNCaP prostate cancer cells.";
RL   Int. J. Biochem. Cell Biol. 54:49-59(2014).
//