ID   LNCaP AR-NTD/pHage
AC   CVCL_A1BN
SY   LNCaPAR-NTD/pHage
DR   Wikidata; Q102114469
RX   PubMed=25008967;
CC   Population: Caucasian.
CC   Characteristics: Inducibly expresses AR N-terminal domain (AR-NTD).
CC   Sequence variation: Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
CC   Transfected with: HGNC; 644; AR (with p.Thr661_Gln920del = AR-NTD).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from metastatic site: Left supraclavicular lymph node.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_1379 ! LNCaP clone FGC
SX   Male
AG   50Y
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 23-06-22; Version: 4
//
RX   PubMed=25008967; DOI=10.1016/j.biocel.2014.06.013;
RA   Krause W.C., Shafi A.A., Nakka M., Weigel N.L.;
RT   "Androgen receptor and its splice variant, AR-V7, differentially
RT   regulate FOXA1 sensitive genes in LNCaP prostate cancer cells.";
RL   Int. J. Biochem. Cell Biol. 54:49-59(2014).
//