ID   Ma-Mel-37b
AC   CVCL_A173
DR   BTO; BTO_0005343
DR   cancercelllines; CVCL_A173
DR   Cosmic; 1846618
DR   Cosmic; 2686401
DR   ESTDAB; ESTDAB-211
DR   Wikidata; Q54903791
RX   PubMed=17311103;
RX   PubMed=23348503;
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
ST   Source(s): ESTDAB=ESTDAB-211
ST   Amelogenin: X
ST   CSF1PO: 8,10
ST   D13S317: 9,11
ST   D3S1358: 14,16
ST   D5S818: 11,13
ST   D7S820: 11,12
ST   FGA: 21,25
ST   TH01: 6,9
ST   TPOX: 8
ST   vWA: 14,17
DI   NCIt; C4225; Cutaneous nodular melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_A172 ! Ma-Mel-37a
SX   Female
AG   59Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 21
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RX   PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595;
RA   Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A.,
RA   Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R.,
RA   Schadendorf D.;
RT   "B-RAF and N-RAS mutations are preserved during short time in vitro
RT   propagation and differentially impact prognosis.";
RL   PLoS ONE 2:e236.1-e236.13(2007).
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RX   PubMed=23348503; DOI=10.1126/science.1230062;
RA   Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A.,
RA   Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.;
RT   "TERT promoter mutations in familial and sporadic melanoma.";
RL   Science 339:959-961(2013).
//