ID   OMC-4
AC   CVCL_A108
SY   OMC4; Osaka Medical College-4
DR   cancercelllines; CVCL_A108
DR   Cosmic; 877474
DR   Cosmic; 1152547
DR   IARC_TP53; 4752
DR   Wikidata; Q54932035
RX   DOI=10.1267/ahc.26.515;
RX   PubMed=2531191;
RX   PubMed=3598280;
RX   PubMed=8380785;
CC   Population: Japanese.
CC   Doubling time: 63 hours (PubMed=3598280).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (PubMed=8380785).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C4029; Cervical adenocarcinoma
DI   ORDO; Orphanet_213772; Adenocarcinoma of the cervix uteri
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   47Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 18
//
RX   DOI=10.1267/ahc.26.515;
RA   Tsuchida K., Okamoto Y., Yamada T., Ueda M., Iijima J., Shiina Y.,
RA   Hirano H., Rokukawa C., Kasama T., Taki T., Handa S., Ueki M.,
RA   Adachi K.;
RT   "Discrimination of metastatic cells from mesothelial cells in effusion
RT   cytology by monoclonal antibody AD117m directed against
RT   lactotetraosylceramide.";
RL   Acta Histochem. Cytochem. 26:515-530(1993).
//
RX   PubMed=2531191;
RA   Ueda M., Misaki O., Yamada T., Okamoto Y., Goto M., Maeda T.,
RA   Okamura S., Ueki M., Sugimoto O.;
RT   "In vitro studies of 5-FU sensitivity on uterine cervical cancer cell
RT   lines -- comparison between squamous cell carcinoma and
RT   adenocarcinoma.";
RL   Nihon Sanka Fujinka Gakkai Zasshi 41:1423-1430(1989).
//
RX   PubMed=3598280;
RA   Yamada T., Ueda M., Maeda T., Miyawaki Y., Misaki O., Ueki M.,
RA   Sugimoto O.;
RT   "Establishment and characterization of a cell line (OMC-4) originating
RT   from a human adenocarcinoma of the uterine cervix.";
RL   Nihon Sanka Fujinka Gakkai Zasshi 39:859-860(1987).
//
RX   PubMed=8380785; DOI=10.1006/gyno.1993.1016;
RA   Iwasaka T., Oh-uchida M., Matsuo N., Yokoyama M., Fukuda K., Hara K.,
RA   Fukuyama K., Hori K., Sugimori H.;
RT   "Correlation between HPV positivity and state of the p53 gene in
RT   cervical carcinoma cell lines.";
RL   Gynecol. Oncol. 48:104-109(1993).
//