ID   CL2621
AC   CVCL_A0XU
SY   CL-2621; CL 2621
DR   Wikidata; Q108820061
RX   Patent=US8546124;
RX   PubMed=1616975;
RX   PubMed=1616976;
RX   PubMed=8507694;
CC   Group: Non-human primate cell line.
CC   Problematic cell line: Misidentified. Parent cell line (MA-104) has been shown to be from Chlorocebus pygerythrus instead of Rhesus macaque.
CC   From: Boehringer Ingelheim Animal Health, Inc.; St. Joseph; USA.
CC   Virology: Susceptible to infection by porcine reproductive and respiratory syndrome virus (PRRSV).
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
OX   NCBI_TaxID=60710; ! Chlorocebus pygerythrus (Vervet monkey)
HI   CVCL_3845 ! MA-104
SX   Sex unspecified
AG   Fetus
CA   Spontaneously immortalized cell line
DT   Created: 23-09-21; Last updated: 19-12-24; Version: 6
//
RX   PubMed=1616975; DOI=10.1177/104063879200400201;
RA   Collins, James Edward
RA   Benfield, David A.
RA   Christianson, William T.
RA   Harris, Louis
RA   Hennings, Jane C.
RA   Shaw, Daniel P.
RA   Goyal, Sagar M.
RA   McCullough, Sam
RA   Morrison, Robert B.
RA   Joo, Han Soo
RA   Gorcyca, David
RA   Chladek, Dan
RT   "Isolation of swine infertility and respiratory syndrome virus
RT   (isolate ATCC VR-2332) in North America and experimental reproduction
RT   of the disease in gnotobiotic pigs.";
RL   J. Vet. Diagn. Invest. 4:117-126(1992).
//
RX   Patent=US8546124;
RA   Meulenberg, Johanna Jacoba Maria
RA   Pol, Johannes Maria Antonius
RA   Bos-de Ruijter, Judy Norma Aletta
RT   "Infectious clones of RNA viruses and vaccines and diagnostic assays
RT   derived thereof.";
RL   Patent number US8546124, 01-Oct-2013.
//
RX   PubMed=8507694; DOI=10.1177/104063879300500204;
RA   Bautista, Elida M.
RA   Goyal, Sagar M.
RA   Yoon, In J.
RA   Joo, Han Soo
RA   Collins, James Edward
RT   "Comparison of porcine alveolar macrophages and CL 2621 for the
RT   detection of porcine reproductive and respiratory syndrome (PRRS)
RT   virus and anti-PRRS antibody.";
RL   J. Vet. Diagn. Invest. 5:163-165(1993).
//
RX   PubMed=1616976; DOI=10.1177/104063879200400202;
RA   Benfield, David A.
RA   Nelson, Eric A.
RA   Collins, James Edward
RA   Harris, Louis
RA   Goyal, Sagar M.
RA   Robison, Deborah
RA   Christianson, William T.
RA   Morrison, Robert B.
RA   Gorcyca, David
RA   Chladek, Dan
RT   "Characterization of swine infertility and respiratory syndrome (SIRS)
RT   virus (isolate ATCC VR-2332).";
RL   J. Vet. Diagn. Invest. 4:127-133(1992).
//