ID   CL2621
AC   CVCL_A0XU
SY   CL-2621; CL 2621
DR   Wikidata; Q108820061
RX   Patent=US8546124;
RX   PubMed=1616975;
RX   PubMed=1616976;
RX   PubMed=8507694;
CC   Group: Non-human primate cell line.
CC   Problematic cell line: Misidentified. Parent cell line (MA-104) has been shown to be from Chlorocebus pygerythrus instead of Rhesus macaque.
CC   From: Boehringer Ingelheim Animal Health, Inc.; St. Joseph; USA.
CC   Virology: Susceptible to infection by porcine reproductive and respiratory syndrome virus (PRRSV).
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=60710; ! Chlorocebus pygerythrus (Vervet monkey)
HI   CVCL_3845 ! MA-104
SX   Sex unspecified
AG   Fetus
CA   Spontaneously immortalized cell line
DT   Created: 23-09-21; Last updated: 29-06-23; Version: 5
//
RX   Patent=US8546124;
RA   Meulenberg J.J.M., Pol J.M.A., Bos-de Ruijter J.N.A.;
RT   "Infectious clones of RNA viruses and vaccines and diagnostic assays
RT   derived thereof.";
RL   Patent number US8546124, 01-Oct-2013.
//
RX   PubMed=1616975; DOI=10.1177/104063879200400201;
RA   Collins J.E., Benfield D.A., Christianson W.T., Harris L.,
RA   Hennings J.C., Shaw D.P., Goyal S.M., McCullough S., Morrison R.B.,
RA   Joo H.S., Gorcyca D., Chladek D.;
RT   "Isolation of swine infertility and respiratory syndrome virus
RT   (isolate ATCC VR-2332) in North America and experimental reproduction
RT   of the disease in gnotobiotic pigs.";
RL   J. Vet. Diagn. Invest. 4:117-126(1992).
//
RX   PubMed=1616976; DOI=10.1177/104063879200400202;
RA   Benfield D.A., Nelson E.A., Collins J.E., Harris L., Goyal S.M.,
RA   Robison D., Christianson W.T., Morrison R.B., Gorcyca D., Chladek D.;
RT   "Characterization of swine infertility and respiratory syndrome (SIRS)
RT   virus (isolate ATCC VR-2332).";
RL   J. Vet. Diagn. Invest. 4:127-133(1992).
//
RX   PubMed=8507694; DOI=10.1177/104063879300500204;
RA   Bautista E.M., Goyal S.M., Yoon I.J., Joo H.S., Collins J.E.;
RT   "Comparison of porcine alveolar macrophages and CL 2621 for the
RT   detection of porcine reproductive and respiratory syndrome (PRRS)
RT   virus and anti-PRRS antibody.";
RL   J. Vet. Diagn. Invest. 5:163-165(1993).
//