ID   A549-CBG
AC   CVCL_A0VZ
DR   cancercelllines; CVCL_A0VZ
DR   Wikidata; Q108819817
RX   PubMed=33537176;
CC   Population: Caucasian.
CC   Characteristics: Transduced with a CBG-T2A-GFP construct.
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transduction; Gene=Click beetle green luciferase (CBG).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 10-04-25; Version: 9
//
RX   PubMed=33537176; DOI=10.1080/2162402X.2021.1873607; PMCID=PMC7833767;
RA   Martinez M., Kim S., St Jean N., O'Brien S., Lian L.-R., Sun J.,
RA   Verona R.I., Moon E.;
RT   "Addition of anti-TIM3 or anti-TIGIT antibodies to anti-PD1 blockade
RT   augments human T cell adoptive cell transfer.";
RL   OncoImmunology 10:e1873607.1-e1873607.16(2021).
//