ID   LAPC4-CR
AC   CVCL_A0BW
DR   cancercelllines; CVCL_A0BW
DR   GEO; GSM5402199
DR   Wikidata; Q108820668
RX   PubMed=34402095;
CC   Characteristics: Derived after 4 passages of the parent cell line in castrated nude mice.
CC   Virology: Contains an integrated xenotropic MuLV-related virus (XMRV) Bxv-1 (from parent cell line).
CC   Doubling time: ~50 hours (PubMed=34402095).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (from parent cell line).
CC   Omics: Proteomics.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4744 ! LAPC-4
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 10-04-25; Version: 10
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RX   PubMed=34402095; DOI=10.1002/pros.24210; PMCID=PMC8460612;
RA   Haffner M.C., Bhamidipati A., Tsai H.K., Esopi D.M., Vaghasia A.M.,
RA   Low J.-Y., Patel R.A., Guner G., Pham M.-T., Castagna N., Hicks J.L.,
RA   Wyhs N., Aebersold R., De Marzo A.M., Nelson W.G., Guo T.-N.,
RA   Yegnasubramanian S.;
RT   "Phenotypic characterization of two novel cell line models of
RT   castration-resistant prostate cancer.";
RL   Prostate 81:1159-1171(2021).
//