ID   CHLA-119
AC   CVCL_A055
DR   cancercelllines; CVCL_A055
DR   Cosmic; 1161984
DR   IARC_TP53; 16197
DR   Wikidata; Q54812153
RX   PubMed=11507071;
RX   PubMed=18724359;
RX   PubMed=20922763;
RX   PubMed=28340497;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg342Leu (c.1025G>T); ClinVar=VCV001055894; Zygosity=Unspecified (PubMed=11507071).
ST   Source(s): COG; PubMed=20922763
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 8,10
ST   D16S539: 9,12
ST   D18S51: 13,17
ST   D19S433: 14
ST   D21S11: 29,30
ST   D2S1338: 19,24
ST   D3S1358: 16,17
ST   D5S818: 12
ST   D7S820: 10,11
ST   D8S1179: 11
ST   FGA: 23,25
ST   TH01: 6,7
ST   TPOX: 8,10
ST   vWA: 14,18
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   4Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 15
//
RX   PubMed=11507071;
RA   Keshelava N., Zuo J.J., Chen P., Waidyaratne S.N., Luna M.C.,
RA   Gomer C.J., Triche T.J., Reynolds C.P.;
RT   "Loss of p53 function confers high-level multidrug resistance in
RT   neuroblastoma cell lines.";
RL   Cancer Res. 61:6185-6193(2001).
//
RX   PubMed=18724359; DOI=10.1038/nature07261; PMCID=PMC2672043;
RA   Mosse Y.P., Laudenslager M., Longo L., Cole K.A., Wood A.,
RA   Attiyeh E.F., Laquaglia M.J., Sennett R., Lynch J.E., Perri P.,
RA   Laureys G., Speleman F., Kim C., Hou C.-P., Hakonarson H., Torkamani A.,
RA   Schork N.J., Brodeur G.M., Tonini G.P., Rappaport E., Devoto M.,
RA   Maris J.M.;
RT   "Identification of ALK as a major familial neuroblastoma
RT   predisposition gene.";
RL   Nature 455:930-935(2008).
//
RX   PubMed=20922763; DOI=10.1002/pbc.22801; PMCID=PMC3005554;
RA   Kang M.H., Smith M.A., Morton C.L., Keshelava N., Houghton P.J.,
RA   Reynolds C.P.;
RT   "National Cancer Institute pediatric preclinical testing program:
RT   model description for in vitro cytotoxicity testing.";
RL   Pediatr. Blood Cancer 56:239-249(2011).
//
RX   PubMed=28340497; DOI=10.1002/ijc.30706;
RA   Lopez-Barcons L., Maurer B.J., Kang M.H., Reynolds C.P.;
RT   "P450 inhibitor ketoconazole increased the intratumor drug levels and
RT   antitumor activity of fenretinide in human neuroblastoma xenograft
RT   models.";
RL   Int. J. Cancer 141:405-413(2017).
//