ID   MEL-STM
AC   CVCL_9U70
DR   Wikidata; Q54905138
RX   PubMed=16142232;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7029; MET (Note=Activated TPR-MET).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
CC   Cell type: Melanocyte of foreskin; CL=CL_2000045.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_C854 ! MEL-STR
OI   CVCL_9U71 ! MEL-STV
SX   Male
AG   <1M
CA   Transformed cell line
DT   Created: 23-02-16; Last updated: 14-08-25; Version: 11
//
RX   PubMed=16142232; DOI=10.1038/ng1634; PMCID=PMC1694635;
RA   Gupta, Piyush B.
RA   Kuperwasser, Charlotte
RA   Brunet, Jean-Philippe
RA   Ramaswamy, Sridhar
RA   Kuo, Wen-Lin
RA   Gray, Joe W.
RA   Naber, Stephen P.
RA   Weinberg, Robert Allan
RT   "The melanocyte differentiation program predisposes to metastasis
RT   after neoplastic transformation.";
RL   Nat. Genet. 37:1047-1054(2005).
//